Wakeham A - Search Results

1

The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.

Lemonnier F, Cairns RA, Inoue S, Li WY, Dupuy A, Broutin S, Martin N, Fataccioli V, Pelletier R, Wakeham A, Snow BE, de Leval L, Pujals A, Haioun C, Paci A, Tobin ER, Narayanaswamy R, Yen K, Jin S, Gaulard P, Mak TW. Lemonnier F, et al. Among authors: wakeham a. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15084-15089. doi: 10.1073/pnas.1617929114. Epub 2016 Dec 12. Proc Natl Acad Sci U S A. 2016. PMID: 27956631 Free PMC article.

2

Differential T cell costimulatory requirements in CD28-deficient mice.

Shahinian A, Pfeffer K, Lee KP, Kündig TM, Kishihara K, Wakeham A, Kawai K, Ohashi PS, Thompson CB, Mak TW. Shahinian A, et al. Among authors: wakeham a. Science. 1993 Jul 30;261(5121):609-12. doi: 10.1126/science.7688139. Science. 1993. PMID: 7688139

3

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection.

Pfeffer K, Matsuyama T, Kündig TM, Wakeham A, Kishihara K, Shahinian A, Wiegmann K, Ohashi PS, Krönke M, Mak TW. Pfeffer K, et al. Among authors: wakeham a. Cell. 1993 May 7;73(3):457-67. doi: 10.1016/0092-8674(93)90134-c. Cell. 1993. PMID: 8387893

4

Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice.

Amakawa R, Hakem A, Kundig TM, Matsuyama T, Simard JJ, Timms E, Wakeham A, Mittruecker HW, Griesser H, Takimoto H, Schmits R, Shahinian A, Ohashi P, Penninger JM, Mak TW. Amakawa R, et al. Among authors: wakeham a. Cell. 1996 Feb 23;84(4):551-62. doi: 10.1016/s0092-8674(00)81031-4. Cell. 1996. PMID: 8598042 Free article.

5

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function.

Mittrücker HW, Matsuyama T, Grossman A, Kündig TM, Potter J, Shahinian A, Wakeham A, Patterson B, Ohashi PS, Mak TW. Mittrücker HW, et al. Among authors: wakeham a. Science. 1997 Jan 24;275(5299):540-3. doi: 10.1126/science.275.5299.540. Science. 1997. PMID: 8999800

6

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.

Yeh WC, Shahinian A, Speiser D, Kraunus J, Billia F, Wakeham A, de la Pompa JL, Ferrick D, Hum B, Iscove N, Ohashi P, Rothe M, Goeddel DV, Mak TW. Yeh WC, et al. Among authors: wakeham a. Immunity. 1997 Nov;7(5):715-25. doi: 10.1016/s1074-7613(00)80391-x. Immunity. 1997. PMID: 9390694 Free article.

7

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production.

Yoshida H, Nishina H, Takimoto H, Marengère LE, Wakeham AC, Bouchard D, Kong YY, Ohteki T, Shahinian A, Bachmann M, Ohashi PS, Penninger JM, Crabtree GR, Mak TW. Yoshida H, et al. Among authors: wakeham ac. Immunity. 1998 Jan;8(1):115-24. doi: 10.1016/s1074-7613(00)80464-1. Immunity. 1998. PMID: 9462517 Free article.

8

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice.

Suzuki A, de la Pompa JL, Stambolic V, Elia AJ, Sasaki T, del Barco Barrantes I, Ho A, Wakeham A, Itie A, Khoo W, Fukumoto M, Mak TW. Suzuki A, et al. Among authors: wakeham a. Curr Biol. 1998 Oct 22;8(21):1169-78. doi: 10.1016/s0960-9822(07)00488-5. Curr Biol. 1998. PMID: 9799734 Free article.

9

DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW. Hirao A, et al. Among authors: wakeham a. Science. 2000 Mar 10;287(5459):1824-7. doi: 10.1126/science.287.5459.1824. Science. 2000. PMID: 10710310

10

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice.

Rudolph D, Yeh WC, Wakeham A, Rudolph B, Nallainathan D, Potter J, Elia AJ, Mak TW. Rudolph D, et al. Among authors: wakeham a. Genes Dev. 2000 Apr 1;14(7):854-62. Genes Dev. 2000. PMID: 10766741 Free PMC article.

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