Yao J - Search Results

1

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.

Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, Yan J, Xie XJ, Sarode V, Williams NS, Minna JD, Beg M, Gerber DE, Bey EA, Boothman DA. Huang X, et al. Among authors: yao j. Cancer Cell. 2016 Dec 12;30(6):940-952. doi: 10.1016/j.ccell.2016.11.006. Cancer Cell. 2016. PMID: 27960087 Free PMC article.

2

EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer.

Yamaguchi H, Du Y, Nakai K, Ding M, Chang SS, Hsu JL, Yao J, Wei Y, Nie L, Jiao S, Chang WC, Chen CH, Yu Y, Hortobagyi GN, Hung MC. Yamaguchi H, et al. Among authors: yao j. Oncogene. 2018 Jan 11;37(2):208-217. doi: 10.1038/onc.2017.311. Epub 2017 Sep 18. Oncogene. 2018. PMID: 28925391 Free PMC article.

3

Targeting polyploid giant cancer cells potentiates a therapeutic response and overcomes resistance to PARP inhibitors in ovarian cancer.

Zhang X, Yao J, Li X, Niu N, Liu Y, Hajek RA, Peng G, Westin S, Sood AK, Liu J. Zhang X, et al. Among authors: yao j. Sci Adv. 2023 Jul 21;9(29):eadf7195. doi: 10.1126/sciadv.adf7195. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478190 Free PMC article.

4

Therapy-Induced Transdifferentiation Promotes Glioma Growth Independent of EGFR Signaling.

Oh H, Hwang I, Jang JY, Wu L, Cao D, Yao J, Ying H, Li JY, Yao Y, Hu B, Wang Q, Zheng H, Paik J. Oh H, et al. Among authors: yao y, yao j. Cancer Res. 2021 Mar 15;81(6):1528-1539. doi: 10.1158/0008-5472.CAN-20-1810. Epub 2021 Jan 28. Cancer Res. 2021. PMID: 33509942

5

Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition.

Yan L, Tu B, Yao J, Gong J, Carugo A, Bristow CA, Wang Q, Zhu C, Dai B, Kang Y, Han L, Feng N, Jin Y, Fleming J, Heffernan TP, Yao W, Ying H. Yan L, et al. Among authors: yao j, yao w. Cancer Res. 2021 Aug 1;81(15):4054-4065. doi: 10.1158/0008-5472.CAN-20-3792. Epub 2021 Jun 11. Cancer Res. 2021. PMID: 34117030 Free PMC article.

6

Overexpression of the c-erbB-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities.

Tan M, Yao J, Yu D. Tan M, et al. Among authors: yao j. Cancer Res. 1997 Mar 15;57(6):1199-205. Cancer Res. 1997. PMID: 9067293

7

Dual inhibition of PI3K signaling and histone deacetylation halts proliferation and induces lethality in mantle cell lymphoma.

Guo H, Zeng D, Zhang H, Bell T, Yao J, Liu Y, Huang S, Li CJ, Lorence E, Zhou S, Gong T, Jiang C, Ahmed M, Yao Y, Nomie KJ, Zhang L, Wang M. Guo H, et al. Among authors: yao y, yao j. Oncogene. 2019 Mar;38(11):1802-1814. doi: 10.1038/s41388-018-0550-3. Epub 2018 Oct 25. Oncogene. 2019. PMID: 30361685

8

BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers.

Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, Chen MK, Alapati A, Yap TA, Hung MC, You MJ, Piwnica-Worms H, Gan B. Lei G, et al. Among authors: yao j. Cancer Discov. 2024 Aug 2;14(8):1476-1495. doi: 10.1158/2159-8290.CD-23-1220. Cancer Discov. 2024. PMID: 38552003

9

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase.

Yu D, Jing T, Liu B, Yao J, Tan M, McDonnell TJ, Hung MC. Yu D, et al. Among authors: yao j. Mol Cell. 1998 Nov;2(5):581-91. doi: 10.1016/s1097-2765(00)80157-4. Mol Cell. 1998. PMID: 9844631 Free article.

10

Tumor promoting properties of the ETS protein MEF in ovarian cancer.

Yao JJ, Liu Y, Lacorazza HD, Soslow RA, Scandura JM, Nimer SD, Hedvat CV. Yao JJ, et al. Oncogene. 2007 Jun 7;26(27):4032-7. doi: 10.1038/sj.onc.1210170. Epub 2007 Jan 8. Oncogene. 2007. PMID: 17213815

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