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Page 1
Early dissemination seeds metastasis in breast cancer.
Hosseini H, Obradović MMS, Hoffmann M, Harper KL, Sosa MS, Werner-Klein M, Nanduri LK, Werno C, Ehrl C, Maneck M, Patwary N, Haunschild G, Gužvić M, Reimelt C, Grauvogl M, Eichner N, Weber F, Hartkopf AD, Taran FA, Brucker SY, Fehm T, Rack B, Buchholz S, Spang R, Meister G, Aguirre-Ghiso JA, Klein CA. Hosseini H, et al. Nature. 2016 Dec 22;540(7634):552-558. doi: 10.1038/nature20785. Epub 2016 Dec 14. Nature. 2016. PMID: 27974799 Free PMC article.
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma.
Werner-Klein M, Scheitler S, Hoffmann M, Hodak I, Dietz K, Lehnert P, Naimer V, Polzer B, Treitschke S, Werno C, Markiewicz A, Weidele K, Czyz Z, Hohenleutner U, Hafner C, Haferkamp S, Berneburg M, Rümmele P, Ulmer A, Klein CA. Werner-Klein M, et al. Nat Commun. 2018 Feb 9;9(1):595. doi: 10.1038/s41467-017-02674-y. Nat Commun. 2018. PMID: 29426936 Free PMC article.
Therapy resistance beyond cellular dormancy.
Werner-Klein M, Klein CA. Werner-Klein M, et al. Nat Cell Biol. 2019 Feb;21(2):117-119. doi: 10.1038/s41556-019-0276-7. Nat Cell Biol. 2019. PMID: 30664787 No abstract available.
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency.
Werner-Klein M, Grujovic A, Irlbeck C, Obradović M, Hoffmann M, Koerkel-Qu H, Lu X, Treitschke S, Köstler C, Botteron C, Weidele K, Werno C, Polzer B, Kirsch S, Gužvić M, Warfsmann J, Honarnejad K, Czyz Z, Feliciello G, Blochberger I, Grunewald S, Schneider E, Haunschild G, Patwary N, Guetter S, Huber S, Rack B, Harbeck N, Buchholz S, Rümmele P, Heine N, Rose-John S, Klein CA. Werner-Klein M, et al. Nat Commun. 2020 Oct 5;11(1):4977. doi: 10.1038/s41467-020-18701-4. Nat Commun. 2020. PMID: 33020483 Free PMC article.
Ex vivo expansion of lung cancer-derived disseminated cancer cells from lymph nodes identifies cells associated with metastatic progression.
Treitschke S, Weidele K, Varadarajan AR, Feliciello G, Warfsmann J, Vorbeck S, Polzer B, Botteron C, Hoffmann M, Dechand V, Mederer T, Weber F, Werner-Klein M, Robold T, Hofmann HS, Werno C, Klein CA. Treitschke S, et al. Among authors: werner klein m. Int J Cancer. 2023 Nov 15;153(10):1854-1867. doi: 10.1002/ijc.34658. Epub 2023 Aug 9. Int J Cancer. 2023. PMID: 37555668
Retrospective cell lineage reconstruction in humans by using short tandem repeats.
Tao L, Raz O, Marx Z, Ghosh MS, Huber S, Greindl-Junghans J, Biezuner T, Amir S, Milo L, Adar R, Levy R, Onn A, Chapal-Ilani N, Berman V, Ben Arie A, Rom G, Oron B, Halaban R, Czyz ZT, Werner-Klein M, Klein CA, Shapiro E. Tao L, et al. Among authors: werner klein m. Cell Rep Methods. 2021 Jul 26;1(3):None. doi: 10.1016/j.crmeth.2021.100054. Cell Rep Methods. 2021. PMID: 34341783 Free PMC article.
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Sorrentino A, Menevse AN, Michels T, Volpin V, Durst FC, Sax J, Xydia M, Hussein A, Stamova S, Spoerl S, Heuschneider N, Muehlbauer J, Jeltsch KM, Rathinasamy A, Werner-Klein M, Breinig M, Mikietyn D, Kohler C, Poschke I, Purr S, Reidell O, Martins Freire C, Offringa R, Gebhard C, Spang R, Rehli M, Boutros M, Schmidl C, Khandelwal N, Beckhove P. Sorrentino A, et al. Among authors: werner klein m. J Immunother Cancer. 2022 May;10(5):e004258. doi: 10.1136/jitc-2021-004258. J Immunother Cancer. 2022. PMID: 35606086 Free PMC article.
18 results