Haider S - Search Results

1

Folding of guanine quadruplex molecules-funnel-like mechanism or kinetic partitioning? An overview from MD simulation studies.

Šponer J, Bussi G, Stadlbauer P, Kührová P, Banáš P, Islam B, Haider S, Neidle S, Otyepka M. Šponer J, et al. Among authors: haider s. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1246-1263. doi: 10.1016/j.bbagen.2016.12.008. Epub 2016 Dec 13. Biochim Biophys Acta Gen Subj. 2017. PMID: 27979677 Free article. Review.

2

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex.

Haider S, Parkinson GN, Neidle S. Haider S, et al. J Mol Biol. 2002 Jul 5;320(2):189-200. doi: 10.1016/S0022-2836(02)00428-X. J Mol Biol. 2002. PMID: 12079378

3

Structure of a G-quadruplex-ligand complex.

Haider SM, Parkinson GN, Neidle S. Haider SM, et al. J Mol Biol. 2003 Feb 7;326(1):117-25. doi: 10.1016/s0022-2836(02)01354-2. J Mol Biol. 2003. PMID: 12547195

4

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.

Harrison RJ, Reszka AP, Haider SM, Romagnoli B, Morrell J, Read MA, Gowan SM, Incles CM, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: haider sm. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5845-9. doi: 10.1016/j.bmcl.2004.09.037. Bioorg Med Chem Lett. 2004. PMID: 15501053

5

Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter.

Todd AK, Haider SM, Parkinson GN, Neidle S. Todd AK, et al. Among authors: haider sm. Nucleic Acids Res. 2007;35(17):5799-808. doi: 10.1093/nar/gkm609. Epub 2007 Aug 24. Nucleic Acids Res. 2007. PMID: 17720713 Free PMC article.

6

Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands.

Cuenca F, Greciano O, Gunaratnam M, Haider S, Munnur D, Nanjunda R, Wilson WD, Neidle S. Cuenca F, et al. Among authors: haider s. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1668-73. doi: 10.1016/j.bmcl.2008.01.050. Epub 2008 Jan 18. Bioorg Med Chem Lett. 2008. PMID: 18243701

7

Molecular dynamics and principal components analysis of human telomeric quadruplex multimers.

Haider S, Parkinson GN, Neidle S. Haider S, et al. Biophys J. 2008 Jul;95(1):296-311. doi: 10.1529/biophysj.107.120501. Epub 2008 Mar 28. Biophys J. 2008. PMID: 18375510 Free PMC article.

8

Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands.

Moorhouse AD, Haider S, Gunaratnam M, Munnur D, Neidle S, Moses JE. Moorhouse AD, et al. Among authors: haider s. Mol Biosyst. 2008 Jun;4(6):629-42. doi: 10.1039/b801822g. Epub 2008 Apr 8. Mol Biosyst. 2008. PMID: 18493662

9

A molecular model for drug binding to tandem repeats of telomeric G-quadruplexes.

Haider SM, Neidle S. Haider SM, et al. Biochem Soc Trans. 2009 Jun;37(Pt 3):583-8. doi: 10.1042/BST0370583. Biochem Soc Trans. 2009. PMID: 19442254

10

Targeting human gastrointestinal stromal tumor cells with a quadruplex-binding small molecule.

Gunaratnam M, Swank S, Haider SM, Galesa K, Reszka AP, Beltran M, Cuenca F, Fletcher JA, Neidle S. Gunaratnam M, et al. Among authors: haider sm. J Med Chem. 2009 Jun 25;52(12):3774-83. doi: 10.1021/jm900424a. J Med Chem. 2009. PMID: 19469547 Free PMC article.

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