Gustafsson MG - Search Results

1

Large-Scale Gene Expression Profiling Platform for Identification of Context-Dependent Drug Responses in Multicellular Tumor Spheroids.

Senkowski W, Jarvius M, Rubin J, Lengqvist J, Gustafsson MG, Nygren P, Kultima K, Larsson R, Fryknäs M. Senkowski W, et al. Among authors: gustafsson mg. Cell Chem Biol. 2016 Nov 17;23(11):1428-1438. doi: 10.1016/j.chembiol.2016.09.013. Epub 2016 Oct 27. Cell Chem Biol. 2016. PMID: 27984028 Free article.

2

Targeting tumor cells based on Phosphodiesterase 3A expression.

Nazir M, Senkowski W, Nyberg F, Blom K, Edqvist PH, Jarvius M, Andersson C, Gustafsson MG, Nygren P, Larsson R, Fryknäs M. Nazir M, et al. Among authors: gustafsson mg. Exp Cell Res. 2017 Dec 15;361(2):308-315. doi: 10.1016/j.yexcr.2017.10.032. Epub 2017 Oct 26. Exp Cell Res. 2017. PMID: 29107068

3

Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer.

Senkowski W, Zhang X, Olofsson MH, Isacson R, Höglund U, Gustafsson M, Nygren P, Linder S, Larsson R, Fryknäs M. Senkowski W, et al. Mol Cancer Ther. 2015 Jun;14(6):1504-16. doi: 10.1158/1535-7163.MCT-14-0792. Epub 2015 Apr 24. Mol Cancer Ther. 2015. PMID: 25911689 Free article.

4

Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles.

Rickardson L, Fryknäs M, Dhar S, Lövborg H, Gullbo J, Rydåker M, Nygren P, Gustafsson MG, Larsson R, Isaksson A. Rickardson L, et al. Among authors: gustafsson mg. Br J Cancer. 2005 Aug 22;93(4):483-92. doi: 10.1038/sj.bjc.6602699. Br J Cancer. 2005. PMID: 16012520 Free PMC article.

5

In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency.

Andersson CR, Fryknäs M, Rickardson L, Larsson R, Isaksson A, Gustafsson MG. Andersson CR, et al. Among authors: gustafsson mg. J Chem Inf Model. 2007 Jan-Feb;47(1):239-48. doi: 10.1021/ci060073n. J Chem Inf Model. 2007. PMID: 17238270

6

In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index.

Kashif M, Andersson C, Hassan S, Karlsson H, Senkowski W, Fryknäs M, Nygren P, Larsson R, Gustafsson MG. Kashif M, et al. Among authors: gustafsson mg. Sci Rep. 2015 Sep 22;5:14118. doi: 10.1038/srep14118. Sci Rep. 2015. PMID: 26392291 Free PMC article.

7

Screening of an annotated compound library for drug activity in a resistant myeloma cell line.

Rickardson L, Fryknäs M, Haglund C, Lövborg H, Nygren P, Gustafsson MG, Isaksson A, Larsson R. Rickardson L, et al. Among authors: gustafsson mg. Cancer Chemother Pharmacol. 2006 Dec;58(6):749-58. doi: 10.1007/s00280-006-0216-7. Epub 2006 Mar 10. Cancer Chemother Pharmacol. 2006. PMID: 16528529

8

Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model.

Fryknäs M, Rickardson L, Wickström M, Dhar S, Lövborg H, Gullbo J, Nygren P, Gustafsson MG, Isaksson A, Larsson R. Fryknäs M, et al. Among authors: gustafsson mg. J Biomol Screen. 2006 Aug;11(5):457-68. doi: 10.1177/1087057106288048. J Biomol Screen. 2006. PMID: 16928983

9

A pragmatic definition of therapeutic synergy suitable for clinically relevant in vitro multicompound analyses.

Kashif M, Andersson C, Åberg M, Nygren P, Sjöblom T, Hammerling U, Larsson R, Gustafsson MG. Kashif M, et al. Among authors: gustafsson mg. Mol Cancer Ther. 2014 Jul;13(7):1964-76. doi: 10.1158/1535-7163.MCT-13-0430. Epub 2014 Apr 22. Mol Cancer Ther. 2014. PMID: 24755197

10

Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing.

Aftab O, Nazir M, Fryknäs M, Hammerling U, Larsson R, Gustafsson MG. Aftab O, et al. Among authors: gustafsson mg. Apoptosis. 2014 Sep;19(9):1411-8. doi: 10.1007/s10495-014-1009-9. Apoptosis. 2014. PMID: 24923770

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