Graham RM - Search Results

1

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

Ngo T, Ilatovskiy AV, Stewart AG, Coleman JL, McRobb FM, Riek RP, Graham RM, Abagyan R, Kufareva I, Smith NJ. Ngo T, et al. Among authors: graham rm. Nat Chem Biol. 2017 Feb;13(2):235-242. doi: 10.1038/nchembio.2266. Epub 2016 Dec 19. Nat Chem Biol. 2017. Retraction in: Nat Chem Biol. 2021 Apr;17(4):501. doi: 10.1038/s41589-021-00746-1 PMID: 27992882 Free PMC article. Retracted.

2

Identification and structural characterization of alpha 1-adrenergic receptor subtypes.

Terman BI, Riek RP, Grodski A, Hess HJ, Graham RM. Terman BI, et al. Among authors: graham rm. Mol Pharmacol. 1990 Apr;37(4):526-34. Mol Pharmacol. 1990. PMID: 2157960

3

A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. II. Purification, characterization, and reconstitution.

Im MJ, Riek RP, Graham RM. Im MJ, et al. Among authors: graham rm. J Biol Chem. 1990 Nov 5;265(31):18952-60. J Biol Chem. 1990. PMID: 2172240 Free article.

4

Evolutionary conservation of both the hydrophilic and hydrophobic nature of transmembrane residues.

Riek RP, Handschumacher MD, Sung SS, Tan M, Glynias MJ, Schluchter MD, Novotny J, Graham RM. Riek RP, et al. Among authors: graham rm. J Theor Biol. 1995 Feb 7;172(3):245-58. doi: 10.1006/jtbi.1995.0021. J Theor Biol. 1995. PMID: 7715195

5

Non-alpha-helical elements modulate polytopic membrane protein architecture.

Riek RP, Rigoutsos I, Novotny J, Graham RM. Riek RP, et al. Among authors: graham rm. J Mol Biol. 2001 Feb 16;306(2):349-62. doi: 10.1006/jmbi.2000.4402. J Mol Biol. 2001. PMID: 11237604

6

Mutation of a single TMVI residue, Phe(282), in the beta(2)-adrenergic receptor results in structurally distinct activated receptor conformations.

Chen S, Lin F, Xu M, Riek RP, Novotny J, Graham RM. Chen S, et al. Among authors: graham rm. Biochemistry. 2002 May 14;41(19):6045-53. doi: 10.1021/bi012189c. Biochemistry. 2002. PMID: 11993999

7

Cross-linking transglutaminases with G protein-coupled receptor signaling.

Iismaa SE, Begg GE, Graham RM. Iismaa SE, et al. Among authors: graham rm. Sci STKE. 2006 Sep 19;2006(353):pe34. doi: 10.1126/stke.3532006pe34. Sci STKE. 2006. PMID: 16985237

8

Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function.

Riek RP, Finch AA, Begg GE, Graham RM. Riek RP, et al. Among authors: graham rm. Mol Pharmacol. 2008 Apr;73(4):1092-104. doi: 10.1124/mol.107.043042. Epub 2008 Jan 17. Mol Pharmacol. 2008. PMID: 18202304

9

The elusive π-helix.

Riek RP, Graham RM. Riek RP, et al. Among authors: graham rm. J Struct Biol. 2011 Jan;173(1):153-60. doi: 10.1016/j.jsb.2010.09.001. Epub 2010 Sep 7. J Struct Biol. 2011. PMID: 20828621

10

RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility.

Yu ZY, Tan JC, McMahon AC, Iismaa SE, Xiao XH, Kesteven SH, Reichelt ME, Mohl MC, Smith NJ, Fatkin D, Allen D, Head SI, Graham RM, Feneley MP. Yu ZY, et al. Among authors: graham rm. PLoS One. 2014 Jun 11;9(6):e99024. doi: 10.1371/journal.pone.0099024. eCollection 2014. PLoS One. 2014. PMID: 24919197 Free PMC article.

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