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Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.
Swaminathan S, Birudukota S, Thakur MK, Parveen R, Kandan S, Juluri S, Shaik S, Anand NN, Burri RR, Kristam R, Hallur MS, Rajagopal S, Schreuder H, Langer T, Rudolph C, Ruf S, Dhakshinamoorthy S, Gosu R, Kannt A. Swaminathan S, et al. Biochem Biophys Res Commun. 2017 Sep 16;491(2):416-422. doi: 10.1016/j.bbrc.2017.07.087. Epub 2017 Jul 15. Biochem Biophys Res Commun. 2017. PMID: 28720493
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Kannt A, Rajagopal S, Kadnur SV, Suresh J, Bhamidipati RK, Swaminathan S, Hallur MS, Kristam R, Elvert R, Czech J, Pfenninger A, Rudolph C, Schreuder H, Chandrasekar DV, Mane VS, Birudukota S, Shaik S, Zope BR, Burri RR, Anand NN, Thakur MK, Singh M, Parveen R, Kandan S, Mullangi R, Yura T, Gosu R, Ruf S, Dhakshinamoorthy S. Kannt A, et al. Among authors: swaminathan s. Sci Rep. 2018 Feb 26;8(1):3660. doi: 10.1038/s41598-018-22081-7. Sci Rep. 2018. PMID: 29483571 Free PMC article.
Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Ruf S, Rajagopal S, Kadnur SV, Hallur MS, Rani S, Kristam R, Swaminathan S, Zope BR, Gondrala PK, Swamy I, Putta VPRK, Kandan S, Zech G, Schreuder H, Rudolph C, Elvert R, Czech J, Birudukota S, Siddiqui MA, Anand NN, Mane VS, Dittakavi S, Suresh J, Gosu R, Ramesh M, Yura T, Dhakshinamoorthy S, Kannt A. Ruf S, et al. Among authors: swaminathan s. Sci Rep. 2022 Sep 14;12(1):15440. doi: 10.1038/s41598-022-19634-2. Sci Rep. 2022. PMID: 36104373 Free PMC article.
The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
Lukacs C, Belunis C, Crowther R, Danho W, Gao L, Goggin B, Janson CA, Li S, Remiszewski S, Schutt A, Thakur MK, Singh SK, Swaminathan S, Pandey R, Tyagi R, Gosu R, Kamath AV, Kuglstatter A. Lukacs C, et al. Among authors: swaminathan s. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1717-25. doi: 10.1107/S0907444913016284. Epub 2013 Aug 15. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23999295 Free PMC article.
Dementia Care Research and Psychosocial Factors.
Morris T, Walker SP, Holder LV, Vaughan E, Petrovsky D, Swaminathan S, Zhao X. Morris T, et al. Among authors: swaminathan s. Alzheimers Dement. 2024 Dec;20 Suppl 4(Suppl 4):e090814. doi: 10.1002/alz.090814. Alzheimers Dement. 2024. PMID: 39782246 Free PMC article.
Comparison of dexmedetomidine versus fentanyl-based total intravenous anesthesia technique on the requirement of propofol, brain relaxation, intracranial pressure, neuronal injury, and hemodynamic parameters in patients with acute traumatic subdural hematoma undergoing emergency craniotomy: A randomized controlled trial.
Chandar Chinnarasan V, Bidkar PU, Swaminathan S, Mani M, Vairappan B, Chatterjee P, Joy JJ, Dey A, Ramadurai R, Gunasekaran A. Chandar Chinnarasan V, et al. Among authors: swaminathan s. Surg Neurol Int. 2024 Dec 13;15:462. doi: 10.25259/SNI_892_2024. eCollection 2024. Surg Neurol Int. 2024. PMID: 39777171 Free PMC article.
Author Correction: Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.
Bailey JI, Puritz CH, Senkow KJ, Markov NS, Diaz E, Jonasson E, Yu Z, Swaminathan S, Lu Z, Fenske S, Grant RA, Abdala-Valencia H, Mylvaganam RJ, Ludwig A, Miller J, Cumming RI, Tighe RM, Gowdy KM, Kalhan R, Jain M, Bharat A, Kurihara C, San Jose Estepar R, San Jose Estepar R, Washko GR, Shilatifard A, Sznajder JI, Ridge KM, Budinger GRS, Braun R, Misharin AV, Sala MA. Bailey JI, et al. Among authors: swaminathan s. Nat Immunol. 2025 Jan 7. doi: 10.1038/s41590-025-02076-z. Online ahead of print. Nat Immunol. 2025. PMID: 39774409 No abstract available.
1,715 results