Herlyn M - Search Results

1

Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in BRCA-Mutant Ovarian Cancer Models.

Kim H, George E, Ragland R, Rafail S, Zhang R, Krepler C, Morgan M, Herlyn M, Brown E, Simpkins F. Kim H, et al. Among authors: herlyn m. Clin Cancer Res. 2017 Jun 15;23(12):3097-3108. doi: 10.1158/1078-0432.CCR-16-2273. Epub 2016 Dec 19. Clin Cancer Res. 2017. PMID: 27993965 Free PMC article.

2

Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck.

Sauter ER, Nesbit M, Watson JC, Klein-Szanto A, Litwin S, Herlyn M. Sauter ER, et al. Among authors: herlyn m. Clin Cancer Res. 1999 Apr;5(4):775-82. Clin Cancer Res. 1999. PMID: 10213212

3

Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion.

Smalley KS, Brafford P, Haass NK, Brandner JM, Brown E, Herlyn M. Smalley KS, et al. Among authors: herlyn m. Am J Pathol. 2005 May;166(5):1541-54. doi: 10.1016/S0002-9440(10)62370-X. Am J Pathol. 2005. PMID: 15855653 Free PMC article.

4

Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression.

Balint K, Xiao M, Pinnix CC, Soma A, Veres I, Juhasz I, Brown EJ, Capobianco AJ, Herlyn M, Liu ZJ. Balint K, et al. Among authors: herlyn m. J Clin Invest. 2005 Nov;115(11):3166-76. doi: 10.1172/JCI25001. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239965 Free PMC article.

5

Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.

Liu ZJ, Xiao M, Balint K, Smalley KS, Brafford P, Qiu R, Pinnix CC, Li X, Herlyn M. Liu ZJ, et al. Among authors: herlyn m. Cancer Res. 2006 Apr 15;66(8):4182-90. doi: 10.1158/0008-5472.CAN-05-3589. Cancer Res. 2006. PMID: 16618740

6

Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma.

Kumar SM, Yu H, Edwards R, Chen L, Kazianis S, Brafford P, Acs G, Herlyn M, Xu X. Kumar SM, et al. Among authors: herlyn m. Cancer Res. 2007 Apr 1;67(7):3177-84. doi: 10.1158/0008-5472.CAN-06-3312. Cancer Res. 2007. PMID: 17409425

7

The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel.

Haass NK, Sproesser K, Nguyen TK, Contractor R, Medina CA, Nathanson KL, Herlyn M, Smalley KS. Haass NK, et al. Among authors: herlyn m. Clin Cancer Res. 2008 Jan 1;14(1):230-9. doi: 10.1158/1078-0432.CCR-07-1440. Clin Cancer Res. 2008. PMID: 18172275

8

Targeting BRAF in advanced melanoma: a first step toward manageable disease.

Vultur A, Villanueva J, Herlyn M. Vultur A, et al. Among authors: herlyn m. Clin Cancer Res. 2011 Apr 1;17(7):1658-63. doi: 10.1158/1078-0432.CCR-10-0174. Epub 2011 Mar 29. Clin Cancer Res. 2011. PMID: 21447722 Free PMC article. Review.

9

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation.

John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. John JK, et al. Among authors: herlyn m. J Invest Dermatol. 2012 Dec;132(12):2818-27. doi: 10.1038/jid.2012.237. Epub 2012 Jul 19. J Invest Dermatol. 2012. PMID: 22810307 Free PMC article.

10

Functional profiling of live melanoma samples using a novel automated platform.

Schayowitz A, Bertenshaw G, Jeffries E, Schatz T, Cotton J, Villanueva J, Herlyn M, Krepler C, Vultur A, Xu W, Yu GH, Schuchter L, Clark DP. Schayowitz A, et al. Among authors: herlyn m. PLoS One. 2012;7(12):e52760. doi: 10.1371/journal.pone.0052760. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23285177 Free PMC article.

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