Rajoli R - Search Results

1

Use of a physiologically based pharmacokinetic model to simulate drug-drug interactions between antineoplastic and antiretroviral drugs.

Moltó J, Rajoli R, Back D, Valle M, Miranda C, Owen A, Clotet B, Siccardi M. Moltó J, et al. Among authors: rajoli r. J Antimicrob Chemother. 2017 Mar 1;72(3):805-811. doi: 10.1093/jac/dkw485. J Antimicrob Chemother. 2017. PMID: 27999009

2

Physiologically Based Pharmacokinetic Modelling to Inform Development of Intramuscular Long-Acting Nanoformulations for HIV.

Rajoli RK, Back DJ, Rannard S, Freel Meyers CL, Flexner C, Owen A, Siccardi M. Rajoli RK, et al. Clin Pharmacokinet. 2015 Jun;54(6):639-50. doi: 10.1007/s40262-014-0227-1. Clin Pharmacokinet. 2015. PMID: 25523214 Free PMC article.

3

Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies.

Moss DM, Marzolini C, Rajoli RK, Siccardi M. Moss DM, et al. Among authors: rajoli rk. Expert Opin Drug Metab Toxicol. 2015;11(8):1203-17. doi: 10.1517/17425255.2015.1037278. Epub 2015 Apr 15. Expert Opin Drug Metab Toxicol. 2015. PMID: 25872900 Review.

4

Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes.

Marzolini C, Rajoli R, Battegay M, Elzi L, Back D, Siccardi M. Marzolini C, et al. Among authors: rajoli r. Clin Pharmacokinet. 2017 Apr;56(4):409-420. doi: 10.1007/s40262-016-0447-7. Clin Pharmacokinet. 2017. PMID: 27599706

5

Efavirenz Is Predicted To Accumulate in Brain Tissue: an In Silico, In Vitro, and In Vivo Investigation.

Curley P, Rajoli RK, Moss DM, Liptrott NJ, Letendre S, Owen A, Siccardi M. Curley P, et al. Among authors: rajoli rk. Antimicrob Agents Chemother. 2016 Dec 27;61(1):e01841-16. doi: 10.1128/AAC.01841-16. Print 2017 Jan. Antimicrob Agents Chemother. 2016. PMID: 27799216 Free PMC article.

6

In Silico Dose Prediction for Long-Acting Rilpivirine and Cabotegravir Administration to Children and Adolescents.

Rajoli RKR, Back DJ, Rannard S, Meyers CF, Flexner C, Owen A, Siccardi M. Rajoli RKR, et al. Clin Pharmacokinet. 2018 Feb;57(2):255-266. doi: 10.1007/s40262-017-0557-x. Clin Pharmacokinet. 2018. PMID: 28540638 Free PMC article.

7

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug-drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART.

Roberts O, Rajoli RKR, Back DJ, Owen A, Darin KM, Fletcher CV, Lamorde M, Scarsi KK, Siccardi M. Roberts O, et al. Among authors: rajoli rkr. J Antimicrob Chemother. 2018 Apr 1;73(4):1004-1012. doi: 10.1093/jac/dkx515. J Antimicrob Chemother. 2018. PMID: 29365101 Free PMC article.

8

Derivation of CYP3A4 and CYP2B6 degradation rate constants in primary human hepatocytes: A siRNA-silencing-based approach.

Chan CYS, Roberts O, Rajoli RKR, Liptrott NJ, Siccardi M, Almond L, Owen A. Chan CYS, et al. Among authors: rajoli rkr. Drug Metab Pharmacokinet. 2018 Aug;33(4):179-187. doi: 10.1016/j.dmpk.2018.01.004. Epub 2018 Mar 16. Drug Metab Pharmacokinet. 2018. PMID: 29921509 Free article.

9

Modelling the long-acting administration of anti-tuberculosis agents using PBPK: a proof of concept study.

Rajoli RKR, Podany AT, Moss DM, Swindells S, Flexner C, Owen A, Siccardi M. Rajoli RKR, et al. Int J Tuberc Lung Dis. 2018 Aug 1;22(8):937-944. doi: 10.5588/ijtld.17.0515. Int J Tuberc Lung Dis. 2018. PMID: 29991405 Free PMC article.

10

Predicting Drug-Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling.

Rajoli RKR, Curley P, Chiong J, Back D, Flexner C, Owen A, Siccardi M. Rajoli RKR, et al. J Infect Dis. 2019 May 5;219(11):1735-1742. doi: 10.1093/infdis/jiy726. J Infect Dis. 2019. PMID: 30566691 Free PMC article.

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