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Iodinated contrast media cause direct tubular cell damage, leading to oxidative stress, low nitric oxide, and impairment of tubuloglomerular feedback.
Liu ZZ, Schmerbach K, Lu Y, Perlewitz A, Nikitina T, Cantow K, Seeliger E, Persson PB, Patzak A, Liu R, Sendeski MM. Liu ZZ, et al. Among authors: liu r. Am J Physiol Renal Physiol. 2014 Apr 15;306(8):F864-72. doi: 10.1152/ajprenal.00302.2013. Epub 2014 Jan 15. Am J Physiol Renal Physiol. 2014. PMID: 24431205 Free PMC article.
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