Kahn CR - Search Results

1

Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.

Sakaguchi M, Fujisaka S, Cai W, Winnay JN, Konishi M, O'Neill BT, Li M, García-Martín R, Takahashi H, Hu J, Kulkarni RN, Kahn CR. Sakaguchi M, et al. Among authors: kahn cr. Cell Metab. 2017 Feb 7;25(2):448-462. doi: 10.1016/j.cmet.2016.12.008. Epub 2017 Jan 5. Cell Metab. 2017. PMID: 28065828 Free PMC article.

2

Alterations in insulin receptor autophosphorylation in insulin resistance: correlation with altered sensitivity to glucose transport and antilipolysis to insulin.

Takayama S, Kahn CR, Kubo K, Foley JE. Takayama S, et al. Among authors: kahn cr. J Clin Endocrinol Metab. 1988 May;66(5):992-9. doi: 10.1210/jcem-66-5-992. J Clin Endocrinol Metab. 1988. PMID: 2834414

3

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity.

White MF, Livingston JN, Backer JM, Lauris V, Dull TJ, Ullrich A, Kahn CR. White MF, et al. Among authors: kahn cr. Cell. 1988 Aug 26;54(5):641-9. doi: 10.1016/s0092-8674(88)80008-4. Cell. 1988. PMID: 2842060

4

The insulin receptor and the molecular mechanism of insulin action.

Kahn CR, White MF. Kahn CR, et al. J Clin Invest. 1988 Oct;82(4):1151-6. doi: 10.1172/JCI113711. J Clin Invest. 1988. PMID: 3049671 Free PMC article. Review. No abstract available.

5

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells.

Brüning JC, Winnay J, Cheatham B, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Mol Cell Biol. 1997 Mar;17(3):1513-21. doi: 10.1128/MCB.17.3.1513. Mol Cell Biol. 1997. PMID: 9032279 Free PMC article.

6

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles.

Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Cell. 1997 Feb 21;88(4):561-72. doi: 10.1016/s0092-8674(00)81896-6. Cell. 1997. PMID: 9038347 Free article.

7

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.

Brüning JC, Michael MD, Winnay JN, Hayashi T, Hörsch D, Accili D, Goodyear LJ, Kahn CR. Brüning JC, et al. Among authors: kahn cr. Mol Cell. 1998 Nov;2(5):559-69. doi: 10.1016/s1097-2765(00)80155-0. Mol Cell. 1998. PMID: 9844629 Free article.

8

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Kulkarni RN, et al. Among authors: kahn cr. Cell. 1999 Feb 5;96(3):329-39. doi: 10.1016/s0092-8674(00)80546-2. Cell. 1999. PMID: 10025399 Free article.

9

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.

Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn CR. Kulkarni RN, et al. Among authors: kahn cr. J Clin Invest. 1999 Dec;104(12):R69-75. doi: 10.1172/JCI8339. J Clin Invest. 1999. PMID: 10606633 Free PMC article.

10

Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts.

Winnay JN, Brüning JC, Burks DJ, Kahn CR. Winnay JN, et al. Among authors: kahn cr. J Biol Chem. 2000 Apr 7;275(14):10545-50. doi: 10.1074/jbc.275.14.10545. J Biol Chem. 2000. PMID: 10744748 Free article.

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