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Mitochondrial β-amyloid in Alzheimer's disease.
Borger E, Aitken L, Muirhead KE, Allen ZE, Ainge JA, Conway SJ, Gunn-Moore FJ. Borger E, et al. Among authors: aitken l. Biochem Soc Trans. 2011 Aug;39(4):868-73. doi: 10.1042/BST0390868. Biochem Soc Trans. 2011. PMID: 21787315
Benzothiazoles - scaffold of interest for CNS targeted drugs.
Hroch L, Aitken L, Benek O, Dolezal M, Kuca K, Gunn-Moore F, Musilek K. Hroch L, et al. Among authors: aitken l. Curr Med Chem. 2015;22(6):730-47. doi: 10.2174/0929867322666141212120631. Curr Med Chem. 2015. PMID: 25515509 Review.
Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
Hroch L, Benek O, Guest P, Aitken L, Soukup O, Janockova J, Musil K, Dohnal V, Dolezal R, Kuca K, Smith TK, Gunn-Moore F, Musilek K. Hroch L, et al. Among authors: aitken l. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3675-8. doi: 10.1016/j.bmcl.2016.05.087. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27287370
252 results