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Page 1
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.
Peirs S, Frismantas V, Matthijssens F, Van Loocke W, Pieters T, Vandamme N, Lintermans B, Dobay MP, Berx G, Poppe B, Goossens S, Bornhauser BC, Bourquin JP, Van Vlierberghe P. Peirs S, et al. Among authors: bourquin jp. Leukemia. 2017 Oct;31(10):2037-2047. doi: 10.1038/leu.2017.10. Epub 2017 Jan 11. Leukemia. 2017. PMID: 28074072 Free article.
Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia.
Dafflon C, Craig VJ, Méreau H, Gräsel J, Schacher Engstler B, Hoffman G, Nigsch F, Gaulis S, Barys L, Ito M, Aguadé-Gorgorió J, Bornhauser B, Bourquin JP, Proske A, Stork-Fux C, Murakami M, Sellers WR, Hofmann F, Schwaller J, Tiedt R. Dafflon C, et al. Among authors: bourquin jp. Leukemia. 2017 Jun;31(6):1269-1277. doi: 10.1038/leu.2016.327. Epub 2016 Nov 14. Leukemia. 2017. PMID: 27840424
CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage.
Slamova L, Starkova J, Fronkova E, Zaliova M, Reznickova L, van Delft FW, Vodickova E, Volejnikova J, Zemanova Z, Polgarova K, Cario G, Figueroa M, Kalina T, Fiser K, Bourquin JP, Bornhauser B, Dworzak M, Zuna J, Trka J, Stary J, Hrusak O, Mejstrikova E. Slamova L, et al. Among authors: bourquin jp. Leukemia. 2014 Mar;28(3):609-20. doi: 10.1038/leu.2013.354. Epub 2013 Nov 25. Leukemia. 2014. PMID: 24270736
RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo.
Jyotsana N, Sharma A, Chaturvedi A, Scherr M, Kuchenbauer F, Sajti L, Barchanski A, Lindner R, Noyan F, Sühs KW, Grote-Koska D, Brand K, Vornlocher HP, Stanulla M, Bornhauser B, Bourquin JP, Eder M, Thol F, Ganser A, Humphries RK, Ramsay E, Cullis P, Heuser M. Jyotsana N, et al. Among authors: bourquin jp. Leukemia. 2018 Jan;32(1):224-226. doi: 10.1038/leu.2017.269. Epub 2017 Aug 22. Leukemia. 2018. PMID: 28827563 Free PMC article. No abstract available.
The CALM-AF10 fusion is a rare event in acute megakaryoblastic leukemia.
Greiner O, Bornhauser BC, Delabesse E, Ballerini P, Landman-Parker J, Bourquin JP. Greiner O, et al. Among authors: bourquin jp. Leukemia. 2007 Dec;21(12):2568-9. doi: 10.1038/sj.leu.2404835. Epub 2007 Jul 5. Leukemia. 2007. PMID: 17611559 No abstract available.
Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment.
Eckert C, Hagedorn N, Sramkova L, Mann G, Panzer-Grümayer R, Peters C, Bourquin JP, Klingebiel T, Borkhardt A, Cario G, Alten J, Escherich G, Astrahantseff K, Seeger K, Henze G, von Stackelberg A. Eckert C, et al. Among authors: bourquin jp. Leukemia. 2015 Aug;29(8):1648-55. doi: 10.1038/leu.2015.59. Epub 2015 Mar 9. Leukemia. 2015. PMID: 25748682
Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy.
Stankov MV, El Khatib M, Kumar Thakur B, Heitmann K, Panayotova-Dimitrova D, Schoening J, Bourquin JP, Schweitzer N, Leverkus M, Welte K, Reinhardt D, Li Z, Orkin SH, Behrens GM, Klusmann JH. Stankov MV, et al. Among authors: bourquin jp. Leukemia. 2014 Mar;28(3):577-88. doi: 10.1038/leu.2013.264. Epub 2013 Sep 12. Leukemia. 2014. PMID: 24080946 Free PMC article.
Additional treatment with 2-Chloro-2-Deoxyadenosine during consolidation in children with high-risk acute myeloid leukemia does not improve survival.
Creutzig U, Dworzak MN, Zimmermann M, Bourquin JP, Gruhn B, Fleischhack G, Graf N, Klingebiel T, Kremens B, Lehrnbecher T, von Neuhoff C, Stackelberg AV, Starý J, Reinhardt D. Creutzig U, et al. Among authors: bourquin jp. Leukemia. 2015 Nov;29(11):2260-3. doi: 10.1038/leu.2015.94. Epub 2015 Apr 14. Leukemia. 2015. PMID: 25869725 Clinical Trial. No abstract available.
An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome.
Harrison CJ, Moorman AV, Schwab C, Carroll AJ, Raetz EA, Devidas M, Strehl S, Nebral K, Harbott J, Teigler-Schlegel A, Zimmerman M, Dastuge N, Baruchel A, Soulier J, Auclerc MF, Attarbaschi A, Mann G, Stark B, Cazzaniga G, Chilton L, Vandenberghe P, Forestier E, Haltrich I, Raimondi SC, Parihar M, Bourquin JP, Tchinda J, Haferlach C, Vora A, Hunger SP, Heerema NA, Haas OA; Ponte di Legno International Workshop in Childhood Acute Lymphoblastic Leukemia. Harrison CJ, et al. Among authors: bourquin jp. Leukemia. 2014 May;28(5):1015-21. doi: 10.1038/leu.2013.317. Epub 2013 Oct 29. Leukemia. 2014. PMID: 24166298 Free PMC article.
CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC.
Tirado-Gonzalez I, Czlonka E, Nevmerzhitskaya A, Soetopo D, Bergonzani E, Mahmoud A, Contreras A, Jeremias I, Platzbecker U, Bourquin JP, Kloz U, Van der Hoeven F, Medyouf H. Tirado-Gonzalez I, et al. Among authors: bourquin jp. Leukemia. 2018 Apr;32(4):1049-1052. doi: 10.1038/leu.2017.346. Epub 2017 Dec 6. Leukemia. 2018. PMID: 29209043 Free PMC article. No abstract available.
157 results