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Page 1
Adenosine analogs bearing phosphate isosteres as human MDO1 ligands.
Zhang Y, Jumppanen M, Maksimainen MM, Auno S, Awol Z, Ghemtio L, Venkannagari H, Lehtiö L, Yli-Kauhaluoma J, Xhaard H, Boije Af Gennäs G. Zhang Y, et al. Among authors: auno s. Bioorg Med Chem. 2018 May 1;26(8):1588-1597. doi: 10.1016/j.bmc.2018.02.006. Epub 2018 Feb 13. Bioorg Med Chem. 2018. PMID: 29501416
Synthesis, Identification, and Structure-Activity Relationship Analysis of GATA4 and NKX2-5 Protein-Protein Interaction Modulators.
Jumppanen M, Kinnunen SM, Välimäki MJ, Talman V, Auno S, Bruun T, Boije Af Gennäs G, Xhaard H, Aumüller IB, Ruskoaho H, Yli-Kauhaluoma J. Jumppanen M, et al. Among authors: auno s. J Med Chem. 2019 Sep 12;62(17):8284-8310. doi: 10.1021/acs.jmedchem.9b01086. Epub 2019 Sep 3. J Med Chem. 2019. PMID: 31431011 Free PMC article.
Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease.
Kilpeläinen TP, Pätsi HT, Svarcbahs R, Julku UH, Eteläinen TS, Cui H, Auno S, Sipari N, Norrbacka S, Leino TO, Jäntti M, Myöhänen TT, Wallén EAA. Kilpeläinen TP, et al. Among authors: auno s. J Med Chem. 2023 Jun 8;66(11):7475-7496. doi: 10.1021/acs.jmedchem.3c00235. Epub 2023 May 29. J Med Chem. 2023. PMID: 37248563 Free PMC article.
5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions.
Pätsi HT, Kilpeläinen TP, Jumppanen M, Uhari-Väänänen J, Wielendaele PV, De Lorenzo F, Cui H, Auno S, Saharinen J, Seppälä E, Sipari N, Savinainen J, De Meester I, Lambeir AM, Lahtela-Kakkonen M, Myöhänen TT, Wallén EAA. Pätsi HT, et al. Among authors: auno s. J Med Chem. 2024 Apr 11;67(7):5421-5436. doi: 10.1021/acs.jmedchem.3c01993. Epub 2024 Mar 28. J Med Chem. 2024. PMID: 38546708 Free PMC article.
14 results