Christrup LL - Search Results

1

Genetic Influences of OPRM1, OPRD1 and COMT on Morphine Analgesia in a Multi-Modal, Multi-Tissue Human Experimental Pain Model.

Nielsen LM, Christrup LL, Sato H, Drewes AM, Olesen AE. Nielsen LM, et al. Among authors: christrup ll. Basic Clin Pharmacol Toxicol. 2017 Jul;121(1):6-12. doi: 10.1111/bcpt.12757. Epub 2017 Mar 14. Basic Clin Pharmacol Toxicol. 2017. PMID: 28084056 Free article. Clinical Trial.

2

The effects of morphine and methylnaltrexone on gastrointestinal pain in healthy male participants.

Brokjaer A, Olesen AE, Christrup LL, Dahan A, Drewes AM. Brokjaer A, et al. Among authors: christrup ll. Neurogastroenterol Motil. 2015 May;27(5):693-704. doi: 10.1111/nmo.12545. Epub 2015 Mar 22. Neurogastroenterol Motil. 2015. PMID: 25810023 Clinical Trial.

3

Cortical and spinal assessment - a comparative study using encephalography and the nociceptive withdrawal reflex.

Fischer IW, Gram M, Hansen TM, Brokjaer A, Graversen C, Malver LP, Mørch CD, Christrup LL, Drewes AM, Olesen AE. Fischer IW, et al. Among authors: christrup ll. J Pharmacol Toxicol Methods. 2017 Mar-Apr;84:37-43. doi: 10.1016/j.vascn.2016.10.008. Epub 2016 Oct 29. J Pharmacol Toxicol Methods. 2017. PMID: 27989852 Clinical Trial.

4

Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics.

Nielsen LM, Sverrisdóttir E, Stage TB, Feddersen S, Brøsen K, Christrup LL, Drewes AM, Olesen AE. Nielsen LM, et al. Among authors: christrup ll. Eur J Pharm Sci. 2017 Mar 1;99:337-342. doi: 10.1016/j.ejps.2016.12.039. Epub 2017 Jan 4. Eur J Pharm Sci. 2017. PMID: 28063968

5

Pharmacokinetic-pharmacodynamic modeling of morphine and oxycodone concentrations and analgesic effect in a multimodal experimental pain model.

Staahl C, Upton R, Foster DJ, Christrup LL, Kristensen K, Hansen SH, Arendt-Nielsen L, Drewes AM. Staahl C, et al. Among authors: christrup ll. J Clin Pharmacol. 2008 May;48(5):619-31. doi: 10.1177/0091270008314465. J Clin Pharmacol. 2008. PMID: 18440921 Clinical Trial.

6

Modelling concentration-analgesia relationships for morphine to evaluate experimental pain models.

Sverrisdóttir E, Foster DJ, Upton RN, Olesen AE, Lund TM, Gabel-Jensen C, Drewes AM, Christrup LL, Kreilgaard M. Sverrisdóttir E, et al. Among authors: christrup ll. Eur J Pharm Sci. 2015 Jan 23;66:50-8. doi: 10.1016/j.ejps.2014.10.003. Epub 2014 Oct 12. Eur J Pharm Sci. 2015. PMID: 25315409 Clinical Trial.

7

Objective markers of the analgesic response to morphine in experimental pain research.

Brokjær A, Olesen AE, Kreilgaard M, Graversen C, Gram M, Christrup LL, Dahan A, Drewes AM. Brokjær A, et al. Among authors: christrup ll. J Pharmacol Toxicol Methods. 2015 May-Jun;73:7-14. doi: 10.1016/j.vascn.2015.01.005. Epub 2015 Feb 7. J Pharmacol Toxicol Methods. 2015. PMID: 25659520 Clinical Trial.

8

A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain.

Sverrisdóttir E, Lund TM, Olesen AE, Drewes AM, Christrup LL, Kreilgaard M. Sverrisdóttir E, et al. Among authors: christrup ll. Eur J Pharm Sci. 2015 Jul 10;74:45-62. doi: 10.1016/j.ejps.2015.03.020. Epub 2015 Apr 7. Eur J Pharm Sci. 2015. PMID: 25861720 Review.

9

Association between Gene Polymorphisms and Pain Sensitivity Assessed in a Multi-Modal Multi-Tissue Human Experimental Model - An Explorative Study.

Nielsen LM, Olesen AE, Sato H, Christrup LL, Drewes AM. Nielsen LM, et al. Among authors: christrup ll. Basic Clin Pharmacol Toxicol. 2016 Oct;119(4):360-6. doi: 10.1111/bcpt.12601. Epub 2016 May 2. Basic Clin Pharmacol Toxicol. 2016. PMID: 27061127 Free article.

10

Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone.

Ladebo L, Abuhelwa AY, Foster DJR, Kroustrup JP, Pacyk GJ, Kongstad KT, Drewes AM, Christrup LL, Olesen AE. Ladebo L, et al. Among authors: christrup ll. Basic Clin Pharmacol Toxicol. 2021 Sep;129(3):232-245. doi: 10.1111/bcpt.13634. Epub 2021 Jul 12. Basic Clin Pharmacol Toxicol. 2021. PMID: 34228875 Free article. Clinical Trial.

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