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A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder.
Ikeda M, Takahashi A, Kamatani Y, Okahisa Y, Kunugi H, Mori N, Sasaki T, Ohmori T, Okamoto Y, Kawasaki H, Shimodera S, Kato T, Yoneda H, Yoshimura R, Iyo M, Matsuda K, Akiyama M, Ashikawa K, Kashiwase K, Tokunaga K, Kondo K, Saito T, Shimasaki A, Kawase K, Kitajima T, Matsuo K, Itokawa M, Someya T, Inada T, Hashimoto R, Inoue T, Akiyama K, Tanii H, Arai H, Kanba S, Ozaki N, Kusumi I, Yoshikawa T, Kubo M, Iwata N. Ikeda M, et al. Among authors: okahisa y. Mol Psychiatry. 2018 Mar;23(3):639-647. doi: 10.1038/mp.2016.259. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115744 Free PMC article. Clinical Trial.
The dysbindin gene (DTNBP1) is associated with methamphetamine psychosis.
Kishimoto M, Ujike H, Motohashi Y, Tanaka Y, Okahisa Y, Kotaka T, Harano M, Inada T, Yamada M, Komiyama T, Hori T, Sekine Y, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Kishimoto M, et al. Among authors: okahisa y. Biol Psychiatry. 2008 Jan 15;63(2):191-6. doi: 10.1016/j.biopsych.2007.03.019. Epub 2007 Jun 6. Biol Psychiatry. 2008. PMID: 17555717
The glycine transporter 1 gene (GLYT1) is associated with methamphetamine-use disorder.
Morita Y, Ujike H, Tanaka Y, Kishimoto M, Okahisa Y, Kotaka T, Harano M, Inada T, Komiyama T, Hori T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. Morita Y, et al. Among authors: okahisa y. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5;147B(1):54-8. doi: 10.1002/ajmg.b.30565. Am J Med Genet B Neuropsychiatr Genet. 2008. PMID: 17582620
Reduced CYP2D6 activity is a negative risk factor for methamphetamine dependence.
Otani K, Ujike H, Sakai A, Okahisa Y, Kotaka T, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Sekine Y, Iwata N, Iyo M, Sora I, Ozaki N, Kuroda S. Otani K, et al. Among authors: okahisa y. Neurosci Lett. 2008 Mar 21;434(1):88-92. doi: 10.1016/j.neulet.2008.01.033. Epub 2008 Jan 19. Neurosci Lett. 2008. PMID: 18280655
Genetic variants of D2 but not D3 or D4 dopamine receptor gene are associated with rapid onset and poor prognosis of methamphetamine psychosis.
Ujike H, Katsu T, Okahisa Y, Takaki M, Kodama M, Inada T, Uchimura N, Yamada M, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Ujike H, et al. Among authors: okahisa y. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Jun 15;33(4):625-9. doi: 10.1016/j.pnpbp.2009.02.019. Epub 2009 Mar 10. Prog Neuropsychopharmacol Biol Psychiatry. 2009. PMID: 19275926
G72 gene is associated with susceptibility to methamphetamine psychosis.
Kotaka T, Ujike H, Okahisa Y, Takaki M, Nakata K, Kodama M, Inada T, Yamada M, Uchimura N, Iwata N, Sora I, Iyo M, Ozaki N, Kuroda S. Kotaka T, et al. Among authors: okahisa y. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Aug 31;33(6):1046-9. doi: 10.1016/j.pnpbp.2009.05.017. Epub 2009 May 29. Prog Neuropsychopharmacol Biol Psychiatry. 2009. PMID: 19482054
71 results