Hylemon PB - Search Results

1

The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice.

Wang Y, Aoki H, Yang J, Peng K, Liu R, Li X, Qiang X, Sun L, Gurley EC, Lai G, Zhang L, Liang G, Nagahashi M, Takabe K, Pandak WM, Hylemon PB, Zhou H. Wang Y, et al. Among authors: hylemon pb. Hepatology. 2017 Jun;65(6):2005-2018. doi: 10.1002/hep.29076. Epub 2017 Apr 28. Hepatology. 2017. PMID: 28120434 Free PMC article.

2

Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes.

Rao YP, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB. Rao YP, et al. Among authors: hylemon pb. Hepatology. 2002 Feb;35(2):307-14. doi: 10.1053/jhep.2002.31104. Hepatology. 2002. PMID: 11826403

3

Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes.

Pandak WM, Hylemon PB, Ren S, Marques D, Gil G, Redford K, Mallonee D, Vlahcevic ZR. Pandak WM, et al. Among authors: hylemon pb. Hepatology. 2002 Jun;35(6):1400-8. doi: 10.1053/jhep.2002.33200. Hepatology. 2002. PMID: 12029625

4

LXR alpha is the dominant regulator of CYP7A1 transcription.

Gupta S, Pandak WM, Hylemon PB. Gupta S, et al. Among authors: hylemon pb. Biochem Biophys Res Commun. 2002 Apr 26;293(1):338-43. doi: 10.1016/S0006-291X(02)00229-2. Biochem Biophys Res Commun. 2002. PMID: 12054605

5

Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes.

Pandak WM, Ren S, Marques D, Hall E, Redford K, Mallonee D, Bohdan P, Heuman D, Gil G, Hylemon P. Pandak WM, et al. J Biol Chem. 2002 Dec 13;277(50):48158-64. doi: 10.1074/jbc.M205244200. Epub 2002 Oct 3. J Biol Chem. 2002. PMID: 12368294 Free article.

6

Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.

Ren S, Marques D, Redford K, Hylemon PB, Gil G, Vlahcevic ZR, Pandak WM. Ren S, et al. Among authors: hylemon pb. Metabolism. 2003 May;52(5):636-42. doi: 10.1053/meta.2003.50106. Metabolism. 2003. PMID: 12759897

7

Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels.

Williams K, Rao YP, Natarajan R, Pandak WM, Hylemon PB. Williams K, et al. Among authors: hylemon pb. Biochem Pharmacol. 2004 Jan 15;67(2):255-67. doi: 10.1016/j.bcp.2003.08.044. Biochem Pharmacol. 2004. PMID: 14698038

8

Effect of increasing the expression of cholesterol transporters (StAR, MLN64, and SCP-2) on bile acid synthesis.

Ren S, Hylemon P, Marques D, Hall E, Redford K, Gil G, Pandak WM. Ren S, et al. J Lipid Res. 2004 Nov;45(11):2123-31. doi: 10.1194/jlr.M400233-JLR200. Epub 2004 Sep 1. J Lipid Res. 2004. PMID: 15342684 Free article.

9

Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes.

Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P. Fang Y, et al. Among authors: hylemon pb. Hepatology. 2004 Oct;40(4):961-71. doi: 10.1002/hep.20385. Hepatology. 2004. PMID: 15382121

10

Overexpression of cholesterol transporter StAR increases in vivo rates of bile acid synthesis in the rat and mouse.

Ren S, Hylemon PB, Marques D, Gurley E, Bodhan P, Hall E, Redford K, Gil G, Pandak WM. Ren S, et al. Among authors: hylemon pb. Hepatology. 2004 Oct;40(4):910-7. doi: 10.1002/hep.20382. Hepatology. 2004. PMID: 15382124

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