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A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.
Fisher FM, Kim M, Doridot L, Cunniff JC, Parker TS, Levine DM, Hellerstein MK, Hudgins LC, Maratos-Flier E, Herman MA. Fisher FM, et al. Among authors: hellerstein mk. Mol Metab. 2016 Nov 23;6(1):14-21. doi: 10.1016/j.molmet.2016.11.008. eCollection 2017 Jan. Mol Metab. 2016. PMID: 28123933 Free PMC article.
A dual sugar challenge test for lipogenic sensitivity to dietary fructose.
Hudgins LC, Parker TS, Levine DM, Hellerstein MK. Hudgins LC, et al. Among authors: hellerstein mk. J Clin Endocrinol Metab. 2011 Mar;96(3):861-8. doi: 10.1210/jc.2010-2007. Epub 2011 Jan 20. J Clin Endocrinol Metab. 2011. PMID: 21252253 Free PMC article. Clinical Trial.
Inhibition of fatty acid synthase with FT-4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non-alcoholic fatty liver disease: Results from two early-phase randomized trials.
Beysen C, Schroeder P, Wu E, Brevard J, Ribadeneira M, Lu W, Dole K, O'Reilly T, Morrow L, Hompesch M, Hellerstein MK, Li K, Johansson L, Kelly PF. Beysen C, et al. Among authors: hellerstein mk. Diabetes Obes Metab. 2021 Mar;23(3):700-710. doi: 10.1111/dom.14272. Epub 2020 Dec 21. Diabetes Obes Metab. 2021. PMID: 33289350 Free PMC article. Clinical Trial.
ER Unfolded Protein Response in Liver In Vivo Is Characterized by Reduced, Not Increased, De Novo Lipogenesis and Cholesterol Synthesis Rates with Uptake of Fatty Acids from Adipose Tissue: Integrated Gene Expression, Translation Rates and Metabolic Fluxes.
Ward CP, Peng L, Yuen S, Chang M, Karapetyan R, Nyangau E, Mohammed H, Palacios H, Ziari N, Joe LK, Frakes AE, Dandan M, Dillin A, Hellerstein MK. Ward CP, et al. Among authors: hellerstein mk. Int J Mol Sci. 2022 Jan 19;23(3):1073. doi: 10.3390/ijms23031073. Int J Mol Sci. 2022. PMID: 35162995 Free PMC article.
302 results