Stein C - Search Results

1

Defibrotide (Defitelio): A New Addition to the Stockpile of Food and Drug Administration-approved Oligonucleotide Drugs.

Stein C, Castanotto D, Krishnan A, Nikolaenko L. Stein C, et al. Mol Ther Nucleic Acids. 2016;5(8):e346. doi: 10.1038/mtna.2016.42. Mol Ther Nucleic Acids. 2016. PMID: 28131276 Free PMC article. No abstract available.

2

Antisense oligonucleotides in cancer.

Castanotto D, Stein CA. Castanotto D, et al. Curr Opin Oncol. 2014 Nov;26(6):584-9. doi: 10.1097/CCO.0000000000000127. Curr Opin Oncol. 2014. PMID: 25188471 Review.

3

Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-mediated Silencing in Mammalian Cells.

Castanotto D, Lin M, Kowolik C, Koch T, Hansen BR, Oerum H, Stein CA. Castanotto D, et al. Among authors: stein ca. Mol Ther. 2016 Jun;24(6):1117-1125. doi: 10.1038/mt.2016.54. Epub 2016 Mar 10. Mol Ther. 2016. PMID: 26961407 Free PMC article.

4

6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells.

Zhang X, Castanotto D, Nam S, Horne D, Stein C. Zhang X, et al. Among authors: stein c. Mol Ther. 2017 Jan 4;25(1):79-91. doi: 10.1016/j.ymthe.2016.10.017. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129131 Free PMC article.

5

FDA-Approved Oligonucleotide Therapies in 2017.

Stein CA, Castanotto D. Stein CA, et al. Mol Ther. 2017 May 3;25(5):1069-1075. doi: 10.1016/j.ymthe.2017.03.023. Epub 2017 Mar 31. Mol Ther. 2017. PMID: 28366767 Free PMC article. Review.

6

Electronic Structures of LNA Phosphorothioate Oligonucleotides.

Bohr HG, Shim I, Stein C, Ørum H, Hansen HF, Koch T. Bohr HG, et al. Among authors: stein c. Mol Ther Nucleic Acids. 2017 Sep 15;8:428-441. doi: 10.1016/j.omtn.2017.05.011. Epub 2017 Jun 1. Mol Ther Nucleic Acids. 2017. PMID: 28918042 Free PMC article.

7

Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis.

Zhang X, Castanotto D, Liu X, Shemi A, Stein CA. Zhang X, et al. Nucleic Acids Res. 2018 Apr 20;46(7):3612-3624. doi: 10.1093/nar/gky150. Nucleic Acids Res. 2018. PMID: 29522198 Free PMC article.

8

Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017-2019.

Rüger J, Ioannou S, Castanotto D, Stein CA. Rüger J, et al. Trends Pharmacol Sci. 2020 Jan;41(1):27-41. doi: 10.1016/j.tips.2019.10.009. Epub 2019 Dec 10. Trends Pharmacol Sci. 2020. PMID: 31836192 Review.

9

A Multifunctional LNA Oligonucleotide-Based Strategy Blocks AR Expression and Transactivation Activity in PCa Cells.

Castanotto D, Zhang X, Rüger J, Alluin J, Sharma R, Pirrotte P, Joenson L, Ioannou S, Nelson MS, Vikeså J, Hansen BR, Koch T, Jensen MA, Rossi JJ, Stein CA. Castanotto D, et al. Mol Ther Nucleic Acids. 2020 Oct 27;23:63-75. doi: 10.1016/j.omtn.2020.10.032. eCollection 2021 Mar 5. Mol Ther Nucleic Acids. 2020. PMID: 33335793 Free PMC article.

10

Phosphorothioates and Me: A Lecture About My 35 Years in Oligo-World on My Receipt of the 2023 Lifetime Achievement Award of the Oligonucleotide Therapeutics Society.

Stein CA. Stein CA. Nucleic Acid Ther. 2024 Aug;34(4):157-163. doi: 10.1089/nat.2024.0032. Epub 2024 Jun 26. Nucleic Acid Ther. 2024. PMID: 38920029 No abstract available.

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