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A 4D view on insulin secretory granule turnover in the β-cell.
Müller A, Mziaut H, Neukam M, Knoch KP, Solimena M. Müller A, et al. Among authors: neukam m. Diabetes Obes Metab. 2017 Sep;19 Suppl 1:107-114. doi: 10.1111/dom.13015. Diabetes Obes Metab. 2017. PMID: 28880479 Review.
Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs.
Kemter E, Müller A, Neukam M, Ivanova A, Klymiuk N, Renner S, Yang K, Broichhagen J, Kurome M, Zakhartchenko V, Kessler B, Knoch KP, Bickle M, Ludwig B, Johnsson K, Lickert H, Kurth T, Wolf E, Solimena M. Kemter E, et al. Among authors: neukam m. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2107665118. doi: 10.1073/pnas.2107665118. Proc Natl Acad Sci U S A. 2021. PMID: 34508004 Free PMC article.
Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL. Binger KJ, et al. Among authors: neukam m. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19983-19988. doi: 10.1073/pnas.1903678116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527264 Free PMC article.
RFX6 Maintains Gene Expression and Function of Adult Human Islet α-Cells.
Coykendall VMN, Qian MF, Tellez K, Bautista A, Bevacqua RJ, Gu X, Hang Y, Neukam M, Zhao W, Chang C, MacDonald PE, Kim SK. Coykendall VMN, et al. Among authors: neukam m. Diabetes. 2024 Mar 1;73(3):448-460. doi: 10.2337/db23-0483. Diabetes. 2024. PMID: 38064570