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Targeted O-glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced-stage bladder tumours.
Cotton S, Azevedo R, Gaiteiro C, Ferreira D, Lima L, Peixoto A, Fernandes E, Neves M, Neves D, Amaro T, Cruz R, Tavares A, Rangel M, Silva AMN, Santos LL, Ferreira JA. Cotton S, et al. Among authors: rangel m. Mol Oncol. 2017 Aug;11(8):895-912. doi: 10.1002/1878-0261.12035. Epub 2017 Mar 2. Mol Oncol. 2017. PMID: 28156048 Free PMC article.
Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension.
Peixoto A, Fernandes E, Gaiteiro C, Lima L, Azevedo R, Soares J, Cotton S, Parreira B, Neves M, Amaro T, Tavares A, Teixeira F, Palmeira C, Rangel M, Silva AM, Reis CA, Santos LL, Oliveira MJ, Ferreira JA. Peixoto A, et al. Among authors: rangel m. Oncotarget. 2016 Sep 27;7(39):63138-63157. doi: 10.18632/oncotarget.11257. Oncotarget. 2016. PMID: 27542232 Free PMC article.
Determining the glycation site specificity of human holo-transferrin.
Silva AMN, Coimbra JTS, Castro MM, Oliveira Â, Brás NF, Fernandes PA, Ramos MJ, Rangel M. Silva AMN, et al. Among authors: rangel m. J Inorg Biochem. 2018 Sep;186:95-102. doi: 10.1016/j.jinorgbio.2018.05.016. Epub 2018 May 26. J Inorg Biochem. 2018. PMID: 29860209
696 results