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Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.
Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJ, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V. Kindler E, et al. Among authors: gaughan c. PLoS Pathog. 2017 Feb 3;13(2):e1006195. doi: 10.1371/journal.ppat.1006195. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28158275 Free PMC article.
Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.
Hong S, Klein EA, Das Gupta J, Hanke K, Weight CJ, Nguyen C, Gaughan C, Kim KA, Bannert N, Kirchhoff F, Munch J, Silverman RH. Hong S, et al. Among authors: gaughan c. J Virol. 2009 Jul;83(14):6995-7003. doi: 10.1128/JVI.00268-09. Epub 2009 Apr 29. J Virol. 2009. PMID: 19403677 Free PMC article.
RNase L triggers autophagy in response to viral infections.
Chakrabarti A, Ghosh PK, Banerjee S, Gaughan C, Silverman RH. Chakrabarti A, et al. Among authors: gaughan c. J Virol. 2012 Oct;86(20):11311-21. doi: 10.1128/JVI.00270-12. Epub 2012 Aug 8. J Virol. 2012. PMID: 22875977 Free PMC article.
RNase L is a negative regulator of cell migration.
Banerjee S, Li G, Li Y, Gaughan C, Baskar D, Parker Y, Lindner DJ, Weiss SR, Silverman RH. Banerjee S, et al. Among authors: gaughan c. Oncotarget. 2015 Dec 29;6(42):44360-72. doi: 10.18632/oncotarget.6246. Oncotarget. 2015. PMID: 26517238 Free PMC article.
OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug.
Banerjee S, Gusho E, Gaughan C, Dong B, Gu X, Holvey-Bates E, Talukdar M, Li Y, Weiss SR, Sicheri F, Saunthararajah Y, Stark GR, Silverman RH. Banerjee S, et al. Among authors: gaughan c. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5071-5076. doi: 10.1073/pnas.1815071116. Epub 2019 Feb 27. Proc Natl Acad Sci U S A. 2019. PMID: 30814222 Free PMC article.
74 results