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PPARγ activation by pioglitazone does not suppress cravings for alcohol, and is associated with a risk of myopathy in treatment seeking alcohol dependent patients: a randomized controlled proof of principle study.
Schwandt ML, Diazgranados N, Umhau JC, Kwako LE, George DT, Heilig M. Schwandt ML, et al. Among authors: umhau jc. Psychopharmacology (Berl). 2020 Aug;237(8):2367-2380. doi: 10.1007/s00213-020-05540-w. Epub 2020 May 22. Psychopharmacology (Berl). 2020. PMID: 32445052 Free PMC article. Clinical Trial.
Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study.
Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, Zhang Y, Shen J, George DT, Hommer D, Heilig M. Umhau JC, et al. Arch Gen Psychiatry. 2010 Oct;67(10):1069-77. doi: 10.1001/archgenpsychiatry.2010.125. Arch Gen Psychiatry. 2010. PMID: 20921123 Free PMC article. Clinical Trial.
47 results