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The targeted eosinophil-lowering effects of dexpramipexole in clinical studies.
Blood Cells Mol Dis. 2017 Mar;63:62-65. doi: 10.1016/j.bcmd.2017.01.008. Epub 2017 Jan 16.
Blood Cells Mol Dis. 2017.
PMID: 28178599
Clinical Trial.
Dexpramipexole as an oral steroid-sparing agent in hypereosinophilic syndromes.
Panch SR, Bozik ME, Brown T, Makiya M, Prussin C, Archibald DG, Hebrank GT, Sullivan M, Sun X, Wetzler L, Ware J, Fay MP, Dunbar CE, Dworetzky SI, Khoury P, Maric I, Klion AD.
Panch SR, et al. Among authors: hebrank gt.
Blood. 2018 Aug 2;132(5):501-509. doi: 10.1182/blood-2018-02-835330. Epub 2018 May 8.
Blood. 2018.
PMID: 29739754
Free PMC article.
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Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size.
Laidlaw TM, Prussin C, Panettieri RA, Lee S, Ferguson BJ, Adappa ND, Lane AP, Palumbo ML, Sullivan M, Archibald D, Dworetzky SI, Hebrank GT, Bozik ME.
Laidlaw TM, et al. Among authors: hebrank gt.
Laryngoscope. 2019 Feb;129(2):E61-E66. doi: 10.1002/lary.27564. Epub 2018 Oct 4.
Laryngoscope. 2019.
PMID: 30284267
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