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Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.
Ma J, Zhang X, Soloveva V, Warren T, Guo F, Wu S, Lu H, Guo J, Su Q, Shen H, Solon E, Comunale MA, Mehta A, Guo JT, Bavari S, Du Y, Block TM, Chang J. Ma J, et al. Among authors: zhang x. Antiviral Res. 2018 Feb;150:112-122. doi: 10.1016/j.antiviral.2017.12.008. Epub 2017 Dec 15. Antiviral Res. 2018. PMID: 29253498 Free PMC article.
Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist.
Zhang X, Liu B, Tang L, Su Q, Hwang N, Sehgal M, Cheng J, Ma J, Zhang X, Tan Y, Zhou Y, Duan Z, DeFilippis VR, Viswanathan U, Kulp J, Du Y, Guo JT, Chang J. Zhang X, et al. ACS Infect Dis. 2019 Jul 12;5(7):1139-1149. doi: 10.1021/acsinfecdis.9b00010. Epub 2019 May 14. ACS Infect Dis. 2019. PMID: 31060350 Free PMC article.
A yellow fever virus NS4B inhibitor not only suppresses viral replication, but also enhances the virus activation of RIG-I-like receptor-mediated innate immune response.
Gao Z, Zhang X, Zhang L, Wu S, Ma J, Wang F, Zhou Y, Dai X, Bullitt E, Du Y, Guo JT, Chang J. Gao Z, et al. Among authors: zhang l, zhang x. PLoS Pathog. 2022 Jan 21;18(1):e1010271. doi: 10.1371/journal.ppat.1010271. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35061864 Free PMC article.
PRMT5 Inhibition Reduces Hyperinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis (HLH).
Brown-Burke F, Saadey R, Mao HCC, Marra P, Brooks E, Wandtke A, Hout I, Leon S, Sharma A, Yasin A, Cash T, Ahmed EH, Baiocchi EJ, Finoti SS, Zhang X, Bhagwat N, Vaddi K, Scherle P, Mozhenkova A, El-Ayachi I, Schenk AD, Sloan SL, Whitman K, Helmig-Mason J, Steyn S, Klimaszewski HL, Weist J, Weigel C, Koirala S, Alinari L, Snyder K, Ranganathan P, Chen CJ, Jordan MB, Baiocchi RA, Shindiapina P. Brown-Burke F, et al. Among authors: zhang x. Blood Adv. 2025 Jan 18:bloodadvances.2024013651. doi: 10.1182/bloodadvances.2024013651. Online ahead of print. Blood Adv. 2025. PMID: 39825858
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