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Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.
Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D. Estoppey D, et al. Among authors: wang q. Sci Rep. 2017 Feb 16;7:42728. doi: 10.1038/srep42728. Sci Rep. 2017. PMID: 28205648 Free PMC article.
Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes.
Ihry RJ, Salick MR, Ho DJ, Sondey M, Kommineni S, Paula S, Raymond J, Henry B, Frias E, Wang Q, Worringer KA, Ye C, Russ C, Reece-Hoyes JS, Altshuler RC, Randhawa R, Yang Z, McAllister G, Hoffman GR, Dolmetsch R, Kaykas A. Ihry RJ, et al. Among authors: wang q. Cell Rep. 2019 Apr 9;27(2):616-630.e6. doi: 10.1016/j.celrep.2019.03.043. Cell Rep. 2019. PMID: 30970262 Free article.
Bile acid analogues are activators of pyrin inflammasome.
Alimov I, Menon S, Cochran N, Maher R, Wang Q, Alford J, Concannon JB, Yang Z, Harrington E, Llamas L, Lindeman A, Hoffman G, Schuhmann T, Russ C, Reece-Hoyes J, Canham SM, Cai X. Alimov I, et al. Among authors: wang q. J Biol Chem. 2019 Mar 8;294(10):3359-3366. doi: 10.1074/jbc.RA118.005103. Epub 2019 Jan 15. J Biol Chem. 2019. PMID: 30647128 Free PMC article.
An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells.
Kobylarz MJ, Goodwin JM, Kang ZB, Annand JW, Hevi S, O'Mahony E, McAllister G, Reece-Hoyes J, Wang Q, Alford J, Russ C, Lindeman A, Beibel M, Roma G, Carbone W, Knehr J, Loureiro J, Antczak C, Wiederschain D, Murphy LO, Menon S, Nyfeler B. Kobylarz MJ, et al. Among authors: wang q. PLoS One. 2020 Aug 24;15(8):e0235551. doi: 10.1371/journal.pone.0235551. eCollection 2020. PLoS One. 2020. PMID: 32833964 Free PMC article.
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