Qiu R - Search Results

1

Utidelone plus capecitabine versus capecitabine alone for heavily pretreated metastatic breast cancer refractory to anthracyclines and taxanes: a multicentre, open-label, superiority, phase 3, randomised controlled trial.

Zhang P, Sun T, Zhang Q, Yuan Z, Jiang Z, Wang XJ, Cui S, Teng Y, Hu XC, Yang J, Pan H, Tong Z, Li H, Yao Q, Wang Y, Yin Y, Sun P, Zheng H, Cheng J, Lu J, Zhang B, Geng C, Liu J, Peng R, Yan M, Zhang S, Huang J, Tang L, Qiu R, Xu B; BG01-1323L study group. Zhang P, et al. Among authors: qiu r. Lancet Oncol. 2017 Mar;18(3):371-383. doi: 10.1016/S1470-2045(17)30088-8. Epub 2017 Feb 11. Lancet Oncol. 2017. PMID: 28209298 Clinical Trial.

2

Phase II trial of utidelone as monotherapy or in combination with capecitabine in heavily pretreated metastatic breast cancer patients.

Zhang P, Tong Z, Tian F, Wang Y, Yang J, Li W, Di L, Liu W, Tang L, Qiu R, Xu B. Zhang P, et al. Among authors: qiu r. J Hematol Oncol. 2016 Aug 11;9(1):68. doi: 10.1186/s13045-016-0297-7. J Hematol Oncol. 2016. PMID: 27516093 Free PMC article. Clinical Trial.

3

Phase I clinical and pharmacokinetic study of UTD1, a genetically engineered epothilone analog in patients with advanced solid tumors.

Zhang P, Sun M, Qiu R, Tang L, Dou G, Xu B. Zhang P, et al. Among authors: qiu r. Cancer Chemother Pharmacol. 2011 Oct;68(4):971-8. doi: 10.1007/s00280-011-1571-6. Epub 2011 Feb 9. Cancer Chemother Pharmacol. 2011. PMID: 21305287 Clinical Trial.

4

Concentration-dependent differential effects of an epothilone analog on cell cycle and p53 signaling.

An F, Zhao WJ, Tang L, Qiu RG. An F, et al. Oncol Rep. 2015 Sep;34(3):1361-8. doi: 10.3892/or.2015.4128. Epub 2015 Jul 14. Oncol Rep. 2015. PMID: 26177745

5

Seamless stitching of biosynthetic gene cluster containing type I polyketide synthases using Red/ET mediated recombination for construction of stably co-existing plasmids.

Su C, Zhao XQ, Wang HN, Qiu RG, Tang L. Su C, et al. Gene. 2015 Jan 10;554(2):233-40. doi: 10.1016/j.gene.2014.10.022. Epub 2014 Oct 11. Gene. 2015. PMID: 25311549

6

Generation of novel epothilone analogs with cytotoxic activity by biotransformation.

Tang L, Qiu RG, Li Y, Katz L. Tang L, et al. J Antibiot (Tokyo). 2003 Jan;56(1):16-23. doi: 10.7164/antibiotics.56.16. J Antibiot (Tokyo). 2003. PMID: 12670045 Free article.

7

Multiple Effects of a Novel Epothilone Analog on Cellular Processes and Signaling Pathways Regulated by Rac1 GTPase in the Human Breast Cancer Cells.

Zhang H, An F, Tang L, Qiu R. Zhang H, et al. Among authors: qiu r. Korean J Physiol Pharmacol. 2014 Apr;18(2):109-20. doi: 10.4196/kjpp.2014.18.2.109. Epub 2014 Apr 3. Korean J Physiol Pharmacol. 2014. PMID: 24757372 Free PMC article.

8

Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells.

Niu M, Sun Y, Liu X, Tang L, Qiu R. Niu M, et al. Among authors: qiu r. J Pharmacol Sci. 2013;121(1):17-24. doi: 10.1254/jphs.12206fp. Epub 2012 Dec 26. J Pharmacol Sci. 2013. PMID: 23269238 Free article.

9

Construction of the co-expression plasmids of fostriecin polyketide synthases and heterologous expression in Streptomyces.

Su C, Zhao X, Qiu R, Tang L. Su C, et al. Among authors: qiu r. Pharm Biol. 2015 Feb;53(2):269-74. doi: 10.3109/13880209.2014.914956. Epub 2014 Nov 27. Pharm Biol. 2015. PMID: 25427408 Free article.

10

Identification of the post-polyketide synthase modification enzymes for fostriecin biosynthesis in Streptomyces pulveraceus.

Liu XJ, Kong RX, Niu MS, Qiu RG, Tang L. Liu XJ, et al. J Nat Prod. 2013 Apr 26;76(4):524-9. doi: 10.1021/np300667r. Epub 2013 Apr 15. J Nat Prod. 2013. PMID: 23586868

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