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The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors.
Lin A, Hu Q, Li C, Xing Z, Ma G, Wang C, Li J, Ye Y, Yao J, Liang K, Wang S, Park PK, Marks JR, Zhou Y, Zhou J, Hung MC, Liang H, Hu Z, Shen H, Hawke DH, Han L, Zhou Y, Lin C, Yang L. Lin A, et al. Among authors: lin c. Nat Cell Biol. 2017 Mar;19(3):238-251. doi: 10.1038/ncb3473. Epub 2017 Feb 20. Nat Cell Biol. 2017. PMID: 28218907 Free PMC article.
A lincRNA switch for embryonic stem cell fate.
Yang L, Lin C, Rosenfeld MG. Yang L, et al. Among authors: lin c. Cell Res. 2011 Dec;21(12):1646-8. doi: 10.1038/cr.2011.166. Epub 2011 Oct 25. Cell Res. 2011. PMID: 22025254 Free PMC article. No abstract available.
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