Shima H - Search Results

1

Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.

Shiroki T, Yokoyama M, Tanuma N, Maejima R, Tamai K, Yamaguchi K, Oikawa T, Noguchi T, Miura K, Fujiya T, Shima H, Sato I, Murata-Kamiya N, Hatakeyama M, Iijima K, Shimosegawa T, Satoh K. Shiroki T, et al. Among authors: shima h. Cancer Sci. 2017 May;108(5):931-940. doi: 10.1111/cas.13211. Epub 2017 Apr 24. Cancer Sci. 2017. PMID: 28235245 Free PMC article.

2

Protein-tyrosine phosphatase PTPepsilon C inhibits Jak-STAT signaling and differentiation induced by interleukin-6 and leukemia inhibitory factor in M1 leukemia cells.

Tanuma N, Nakamura K, Shima H, Kikuchi K. Tanuma N, et al. Among authors: shima h. J Biol Chem. 2000 Sep 8;275(36):28216-21. doi: 10.1074/jbc.M003661200. J Biol Chem. 2000. PMID: 10859312 Free article.

3

Up-regulation of I-2(PP2A)/SET gene expression in rat primary hepatomas and regenerating livers.

Fukukawa C, Shima H, Tanuma N, Ogawa K, Kikuchi K. Fukukawa C, et al. Among authors: shima h. Cancer Lett. 2000 Dec 8;161(1):89-95. doi: 10.1016/s0304-3835(00)00598-x. Cancer Lett. 2000. PMID: 11078917

4

Protein tyrosine phosphatase epsilonC selectively inhibits interleukin-6- and interleukin- 10-induced JAK-STAT signaling.

Tanuma N, Shima H, Nakamura K, Kikuchi K. Tanuma N, et al. Among authors: shima h. Blood. 2001 Nov 15;98(10):3030-4. doi: 10.1182/blood.v98.10.3030. Blood. 2001. PMID: 11698287 Free article.

5

Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo.

Mitsuhashi S, Shima H, Tanuma N, Matsuura N, Takekawa M, Urano T, Kataoka T, Ubukata M, Kikuchi K. Mitsuhashi S, et al. Among authors: shima h. J Biol Chem. 2003 Jan 3;278(1):82-8. doi: 10.1074/jbc.M208888200. Epub 2002 Oct 8. J Biol Chem. 2003. PMID: 12374792 Free article.

6

Reduced tumorigenicity of murine leukemia cells expressing protein-tyrosine phosphatase, PTPepsilon C.

Tanuma N, Shima H, Shimada S, Kikuchi K. Tanuma N, et al. Among authors: shima h. Oncogene. 2003 Mar 27;22(12):1758-62. doi: 10.1038/sj.onc.1206267. Oncogene. 2003. PMID: 12660811

7

Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38.

Takagaki K, Satoh T, Tanuma N, Masuda K, Takekawa M, Shima H, Kikuchi K. Takagaki K, et al. Among authors: shima h. Biochem J. 2004 Nov 1;383(Pt. 3):447-55. doi: 10.1042/BJ20040498. Biochem J. 2004. PMID: 15281913 Free PMC article.

8

Analysis of isoform specific function of PP1 catalytic subunits in mammalian cells using siRNA.

Okada T, Fujii T, Tanuma N, Mitsuhashi S, Urano T, Araki Y, Shima H, Kikuchi K. Okada T, et al. Among authors: shima h. Int J Oncol. 2004 Nov;25(5):1383-8. Int J Oncol. 2004. PMID: 15492829

9

The oncoprotein I-2PP2A/SET negatively regulates the MEK/ERK pathway and cell proliferation.

Fukukawa C, Shima H, Tanuma N, Okada T, Kato N, Adachi Y, Kikuchi K. Fukukawa C, et al. Among authors: shima h. Int J Oncol. 2005 Mar;26(3):751-6. Int J Oncol. 2005. PMID: 15703833

10

pp32/ I-1(PP2A) negatively regulates the Raf-1/MEK/ERK pathway.

Fukukawa C, Tanuma N, Okada T, Kikuchi K, Shima H. Fukukawa C, et al. Among authors: shima h. Cancer Lett. 2005 Aug 26;226(2):155-60. doi: 10.1016/j.canlet.2004.11.026. Epub 2004 Dec 16. Cancer Lett. 2005. PMID: 16039954

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