Grünberg JR - Search Results

1

Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.

Grünberg JR, Hoffmann JM, Hedjazifar S, Nerstedt A, Jenndahl L, Elvin J, Castellot J, Wei L, Movérare-Skrtic S, Ohlsson C, Holm LM, Bäckhed F, Syed I, Bosch F, Saghatelian A, Kahn BB, Hammarstedt A, Smith U. Grünberg JR, et al. Sci Rep. 2017 Feb 27;7:43515. doi: 10.1038/srep43515. Sci Rep. 2017. PMID: 28240264 Free PMC article.

2

The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT.

Grünberg JR, Hammarstedt A, Hedjazifar S, Smith U. Grünberg JR, et al. J Biol Chem. 2014 Mar 7;289(10):6899-6907. doi: 10.1074/jbc.M113.511964. Epub 2014 Jan 22. J Biol Chem. 2014. PMID: 24451367 Free PMC article.

3

BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue.

Hoffmann JM, Grünberg JR, Church C, Elias I, Palsdottir V, Jansson JO, Bosch F, Hammarstedt A, Hedjazifar S, Smith U. Hoffmann JM, et al. Among authors: grunberg jr. Cell Rep. 2017 Aug 1;20(5):1038-1049. doi: 10.1016/j.celrep.2017.07.020. Cell Rep. 2017. PMID: 28768190 Free article.

4

BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice.

Hoffmann JM, Grünberg JR, Hammarstedt A, Kroon T, Greiner TU, Maurer S, Elias I, Palsdottir V, Bosch F, Boucher J, Hedjazifar S, Smith U. Hoffmann JM, et al. Among authors: grunberg jr. Mol Metab. 2020 Feb;32:15-26. doi: 10.1016/j.molmet.2019.11.016. Epub 2019 Dec 17. Mol Metab. 2020. PMID: 32029225 Free PMC article.

5

CCN5/WISP2 and metabolic diseases.

Grünberg JR, Elvin J, Paul A, Hedjazifar S, Hammarstedt A, Smith U. Grünberg JR, et al. J Cell Commun Signal. 2018 Mar;12(1):309-318. doi: 10.1007/s12079-017-0437-z. Epub 2017 Dec 15. J Cell Commun Signal. 2018. PMID: 29247377 Free PMC article. Review.

6

WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.

Hammarstedt A, Hedjazifar S, Jenndahl L, Gogg S, Grünberg J, Gustafson B, Klimcakova E, Stich V, Langin D, Laakso M, Smith U. Hammarstedt A, et al. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2563-8. doi: 10.1073/pnas.1211255110. Epub 2013 Jan 28. Proc Natl Acad Sci U S A. 2013. PMID: 23359679 Free PMC article.

7

Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis.

Walter J, Schindzielorz A, Grünberg J, Haass C. Walter J, et al. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1391-6. doi: 10.1073/pnas.96.4.1391. Proc Natl Acad Sci U S A. 1999. PMID: 9990034 Free PMC article.

8

Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.

Walter J, Grünberg J, Capell A, Pesold B, Schindzielorz A, Citron M, Mendla K, George-Hyslop PS, Multhaup G, Selkoe DJ, Haass C. Walter J, et al. Proc Natl Acad Sci U S A. 1997 May 13;94(10):5349-54. doi: 10.1073/pnas.94.10.5349. Proc Natl Acad Sci U S A. 1997. PMID: 9144240 Free PMC article.

9

The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells.

Ungerbäck J, Elander N, Grünberg J, Sigvardsson M, Söderkvist P. Ungerbäck J, et al. PLoS One. 2011 Mar 18;6(3):e17957. doi: 10.1371/journal.pone.0017957. PLoS One. 2011. PMID: 21437251 Free PMC article.

10

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.

Capell A, Grünberg J, Pesold B, Diehlmann A, Citron M, Nixon R, Beyreuther K, Selkoe DJ, Haass C. Capell A, et al. J Biol Chem. 1998 Feb 6;273(6):3205-11. doi: 10.1074/jbc.273.6.3205. J Biol Chem. 1998. PMID: 9452432 Free article.

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