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Page 1
Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers.
Fuller FD, Gul S, Chatterjee R, Burgie ES, Young ID, Lebrette H, Srinivas V, Brewster AS, Michels-Clark T, Clinger JA, Andi B, Ibrahim M, Pastor E, de Lichtenberg C, Hussein R, Pollock CJ, Zhang M, Stan CA, Kroll T, Fransson T, Weninger C, Kubin M, Aller P, Lassalle L, Bräuer P, Miller MD, Amin M, Koroidov S, Roessler CG, Allaire M, Sierra RG, Docker PT, Glownia JM, Nelson S, Koglin JE, Zhu D, Chollet M, Song S, Lemke H, Liang M, Sokaras D, Alonso-Mori R, Zouni A, Messinger J, Bergmann U, Boal AK, Bollinger JM Jr, Krebs C, Högbom M, Phillips GN Jr, Vierstra RD, Sauter NK, Orville AM, Kern J, Yachandra VK, Yano J. Fuller FD, et al. Among authors: orville am. Nat Methods. 2017 Apr;14(4):443-449. doi: 10.1038/nmeth.4195. Epub 2017 Feb 27. Nat Methods. 2017. PMID: 28250468 Free PMC article.
Acoustically mounted microcrystals yield high-resolution X-ray structures.
Soares AS, Engel MA, Stearns R, Datwani S, Olechno J, Ellson R, Skinner JM, Allaire M, Orville AM. Soares AS, et al. Among authors: orville am. Biochemistry. 2011 May 31;50(21):4399-401. doi: 10.1021/bi200549x. Epub 2011 May 9. Biochemistry. 2011. PMID: 21542590 Free PMC article.
Macromolecular crystallography beamline X25 at the NSLS.
Héroux A, Allaire M, Buono R, Cowan ML, Dvorak J, Flaks L, Lamarra S, Myers SF, Orville AM, Robinson HH, Roessler CG, Schneider DK, Shea-McCarthy G, Skinner JM, Skinner M, Soares AS, Sweet RM, Berman LE. Héroux A, et al. Among authors: orville am. J Synchrotron Radiat. 2014 May;21(Pt 3):627-32. doi: 10.1107/S1600577514003415. Epub 2014 Apr 8. J Synchrotron Radiat. 2014. PMID: 24763654 Free PMC article.
Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes.
Yin X, Scalia A, Leroy L, Cuttitta CM, Polizzo GM, Ericson DL, Roessler CG, Campos O, Ma MY, Agarwal R, Jackimowicz R, Allaire M, Orville AM, Sweet RM, Soares AS. Yin X, et al. Among authors: orville am. Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1177-89. doi: 10.1107/S1399004713034603. Epub 2014 Apr 30. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24816088 Free PMC article.
A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection.
Cole K, Roessler CG, Mulé EA, Benson-Xu EJ, Mullen JD, Le BA, Tieman AM, Birone C, Brown M, Hernandez J, Neff S, Williams D, Allaire M, Orville AM, Sweet RM, Soares AS. Cole K, et al. Among authors: orville am. PLoS One. 2014 Jul 2;9(7):e101036. doi: 10.1371/journal.pone.0101036. eCollection 2014. PLoS One. 2014. PMID: 24988328 Free PMC article.
Solvent minimization induces preferential orientation and crystal clustering in serial micro-crystallography on micro-meshes, in situ plates and on a movable crystal conveyor belt.
Soares AS, Mullen JD, Parekh RM, McCarthy GS, Roessler CG, Jackimowicz R, Skinner JM, Orville AM, Allaire M, Sweet RM. Soares AS, et al. Among authors: orville am. J Synchrotron Radiat. 2014 Nov;21(Pt 6):1231-9. doi: 10.1107/S1600577514017731. Epub 2014 Oct 9. J Synchrotron Radiat. 2014. PMID: 25343789 Free PMC article.
Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening.
Cuttitta CM, Ericson DL, Scalia A, Roessler CG, Teplitsky E, Joshi K, Campos O, Agarwal R, Allaire M, Orville AM, Sweet RM, Soares AS. Cuttitta CM, et al. Among authors: orville am. Acta Crystallogr D Biol Crystallogr. 2015 Jan 1;71(Pt 1):94-103. doi: 10.1107/S1399004714013728. Epub 2015 Jan 1. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25615864 Free PMC article.
88 results