Asahi S - Search Results

1

Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Furukawa Y, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S. Goto A, et al. Among authors: asahi s. Biopharm Drug Dispos. 2017 Sep;38(6):373-380. doi: 10.1002/bdd.2075. Epub 2017 May 23. Biopharm Drug Dispos. 2017. PMID: 28256717

2

Species differences of organic anion transporters involved in the renal uptake of 4-amino-3-chlorophenyl hydrogen sulfate, a metabolite of resatorvid, between rats and dogs.

Takeuchi T, Jinno F, Ebihara T, Moriya Y, Kadotani R, Tagawa Y, Kondo T, Itoh T, Asahi S. Takeuchi T, et al. Among authors: asahi s. Biopharm Drug Dispos. 2013 May;34(4):236-46. doi: 10.1002/bdd.1841. Epub 2013 May 7. Biopharm Drug Dispos. 2013. PMID: 23529922

3

The effects of the concentration-dependent erythrocyte distribution of TAK-802, a potent acetylcholinesterase inhibitor, on rat pharmacokinetics.

Kakehi M, Tagawa Y, Goto A, Kondo T, Asahi S. Kakehi M, et al. Among authors: asahi s. Biopharm Drug Dispos. 2016 Nov;37(8):467-478. doi: 10.1002/bdd.2029. Epub 2016 Sep 26. Biopharm Drug Dispos. 2016. PMID: 27554287

4

Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Yamamoto M, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S. Goto A, et al. Among authors: asahi s. Biopharm Drug Dispos. 2017 Dec;38(9):543-552. doi: 10.1002/bdd.2106. Epub 2017 Nov 9. Biopharm Drug Dispos. 2017. PMID: 28948605

5

Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK-448, for its anti-tumor efficacy in a rat xenograft model.

Kogame A, Ishikawa K, DeJongh J, Tagawa Y, Matsui H, Moriya Y, Kondo T, Asahi S. Kogame A, et al. Among authors: asahi s. Biopharm Drug Dispos. 2020 Jul;41(7):283-294. doi: 10.1002/bdd.2245. Epub 2020 Jul 16. Biopharm Drug Dispos. 2020. PMID: 32562504

6

Disposition of the Highly Fat Distributed Compound 1-(4-Methoxyphenyl)-4-(2,2,4,6,7-Pentamethyl -2,3-Dihydro-1-Benzofuran-5-yl)Piperazine (TAK-357) in Rats and Dogs.

Goto A, Moriya Y, Mandai T, Wakabayashi T, Tsukamoto T, Tagawa Y, Kondo T, Asahi S. Goto A, et al. Among authors: asahi s. Drug Res (Stuttg). 2017 Jan;67(1):38-45. doi: 10.1055/s-0042-117624. Epub 2016 Oct 11. Drug Res (Stuttg). 2017. PMID: 27728931

7

Differences in the pharmacokinetics of 4-amino-3-chlorophenyl hydrogen sulfate, a metabolite of resatorvid, in rats and dogs.

Jinno F, Takeuchi T, Tagawa Y, Kondo T, Itoh T, Asahi S. Jinno F, et al. Among authors: asahi s. Drug Metab Dispos. 2012 Apr;40(4):648-54. doi: 10.1124/dmd.111.043729. Epub 2011 Dec 27. Drug Metab Dispos. 2012. PMID: 22203697

8

Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs.

Kogame A, Takeuchi T, Nonaka M, Yamasaki H, Kawaguchi N, Bernards A, Tagawa Y, Morohashi A, Kondo T, Moriwaki T, Asahi S. Kogame A, et al. Among authors: asahi s. Xenobiotica. 2017 Mar;47(3):255-266. doi: 10.1080/00498254.2016.1182667. Epub 2016 May 26. Xenobiotica. 2017. PMID: 27225050

9

Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins.

Narita N, Morohashi A, Tohyama K, Takeuchi T, Tagawa Y, Kondo T, Asahi S. Narita N, et al. Among authors: asahi s. Drug Metab Dispos. 2018 Mar;46(3):204-213. doi: 10.1124/dmd.117.078782. Epub 2017 Dec 21. Drug Metab Dispos. 2018. PMID: 29269409

10

Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S. Moriya Y, et al. Among authors: asahi s. Xenobiotica. 2019 Jul;49(7):833-839. doi: 10.1080/00498254.2018.1499152. Epub 2018 Sep 12. Xenobiotica. 2019. PMID: 30044673

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