DeJongh J - Search Results

1

Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Furukawa Y, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S. Goto A, et al. Among authors: dejongh j. Biopharm Drug Dispos. 2017 Sep;38(6):373-380. doi: 10.1002/bdd.2075. Epub 2017 May 23. Biopharm Drug Dispos. 2017. PMID: 28256717

2

Population pharmacokinetic model of the pregabalin-sildenafil interaction in rats: application of simulation to preclinical PK-PD study design.

Bender G, Gosset J, Florian J, Tan K, Field M, Marshall S, DeJongh J, Bies R, Danhof M. Bender G, et al. Among authors: dejongh j. Pharm Res. 2009 Oct;26(10):2259-69. doi: 10.1007/s11095-009-9942-y. Epub 2009 Aug 11. Pharm Res. 2009. PMID: 19669867 Free PMC article.

3

Pharmacokinetic-pharmacodynamic modeling of alpha interferon response induced by a Toll-like 7 receptor agonist in mice.

Benson N, de Jongh J, Duckworth JD, Jones HM, Pertinez HE, Rawal JK, van Steeg TJ, Van der Graaf PH. Benson N, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1179-85. doi: 10.1128/AAC.00551-09. Epub 2009 Dec 22. Antimicrob Agents Chemother. 2010. PMID: 20028817 Free PMC article.

4

Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Yamamoto M, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S. Goto A, et al. Among authors: dejongh j. Biopharm Drug Dispos. 2017 Dec;38(9):543-552. doi: 10.1002/bdd.2106. Epub 2017 Nov 9. Biopharm Drug Dispos. 2017. PMID: 28948605

5

Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK-448, for its anti-tumor efficacy in a rat xenograft model.

Kogame A, Ishikawa K, DeJongh J, Tagawa Y, Matsui H, Moriya Y, Kondo T, Asahi S. Kogame A, et al. Among authors: dejongh j. Biopharm Drug Dispos. 2020 Jul;41(7):283-294. doi: 10.1002/bdd.2245. Epub 2020 Jul 16. Biopharm Drug Dispos. 2020. PMID: 32562504

6

Simulation of toluene kinetics in the rat by a physiologically based pharmacokinetic model with application of biotransformation parameters derived independently in vitro and in vivo.

DeJongh J, Blaauboer BJ. DeJongh J, et al. Fundam Appl Toxicol. 1996 Aug;32(2):260-8. doi: 10.1006/faat.1996.0129. Fundam Appl Toxicol. 1996. PMID: 8921329

7

A human physiologically-based model for glycyrrhzic acid, a compound subject to presystemic metabolism and enterohepatic cycling.

Ploeger B, Mensinga T, Sips A, Meulenbelt J, DeJongh J. Ploeger B, et al. Among authors: dejongh j. Pharm Res. 2000 Dec;17(12):1516-25. doi: 10.1023/a:1007661209921. Pharm Res. 2000. PMID: 11303962 Clinical Trial.

8

The pharmacokinetics of glycyrrhizic acid evaluated by physiologically based pharmacokinetic modeling.

Ploeger B, Mensinga T, Sips A, Seinen W, Meulenbelt J, DeJongh J. Ploeger B, et al. Among authors: dejongh j. Drug Metab Rev. 2001 May;33(2):125-47. doi: 10.1081/dmr-100104400. Drug Metab Rev. 2001. PMID: 11495500 Review.

9

Pharmacokinetics of recombinant human antithrombin in delivery and surgery patients with hereditary antithrombin deficiency.

DeJongh J, Frieling J, Lowry S, Drenth HJ. DeJongh J, et al. Clin Appl Thromb Hemost. 2014 May;20(4):355-64. doi: 10.1177/1076029613516188. Epub 2013 Dec 11. Clin Appl Thromb Hemost. 2014. PMID: 24335249 Free article. Clinical Trial.

10

Simulation of lindane kinetics in rats.

DeJongh J, Blaauboer BJ. DeJongh J, et al. Toxicology. 1997 Sep 26;122(1-2):1-9. doi: 10.1016/s0300-483x(97)00070-x. Toxicology. 1997. PMID: 9274797

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