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Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure.
Cuschieri J, Bulger E, Schaeffer V, Sakr S, Nathens AB, Hennessy L, Minei J, Moore EE, O'Keefe G, Sperry J, Remick D, Tompkins R, Maier RV; Inflammation and the Host Response to Injury Collaborative Research Program. Cuschieri J, et al. Among authors: bulger e. Shock. 2010 Oct;34(4):346-51. doi: 10.1097/SHK.0b013e3181d8e687. Shock. 2010. PMID: 20844410 Free PMC article.
Increased platelet:RBC ratios are associated with improved survival after massive transfusion.
Holcomb JB, Zarzabal LA, Michalek JE, Kozar RA, Spinella PC, Perkins JG, Matijevic N, Dong JF, Pati S, Wade CE; Trauma Outcomes Group; Holcomb JB, Wade CE, Cotton BA, Kozar RA, Brasel KJ, Vercruysse GA, MacLeod JB, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat PC, Johannigamn JA, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, DeMoya MA, Schreiber MA, Tieu BH, Brundage SI, Napolitano LM, Brunsvold ME, Sihler KC, Beilman GJ, Peitzman AB, Zenati MS, Sperry JL, Alarcon LH, Croce MA, Minei JP, Steward RM, Cohn SM, Michalek JE, Bulger EM, Nunez TC, Ivatury RR, Meredith JW, Miller PR, Pomper GJ, Marin B. Holcomb JB, et al. Among authors: bulger em. J Trauma. 2011 Aug;71(2 Suppl 3):S318-28. doi: 10.1097/TA.0b013e318227edbb. J Trauma. 2011. PMID: 21814099
High ratios of plasma and platelets to packed red blood cells do not affect mortality in nonmassively transfused patients.
Sambasivan CN, Kunio NR, Nair PV, Zink KA, Michalek JE, Holcomb JB, Schreiber MA; Trauma Outcomes Group; Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Sambasivan CN, et al. Among authors: bulger em. J Trauma. 2011 Aug;71(2 Suppl 3):S329-36. doi: 10.1097/TA.0b013e318227edd3. J Trauma. 2011. PMID: 21814100
429 results