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Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.
Guix FX, Sannerud R, Berditchevski F, Arranz AM, Horré K, Snellinx A, Thathiah A, Saido T, Saito T, Rajesh S, Overduin M, Kumar-Singh S, Radaelli E, Corthout N, Colombelli J, Tosi S, Munck S, Salas IH, Annaert W, De Strooper B. Guix FX, et al. Mol Neurodegener. 2017 Mar 10;12(1):25. doi: 10.1186/s13024-017-0165-0. Mol Neurodegener. 2017. PMID: 28279219 Free PMC article.
Alterations in phosphatidylethanolamine levels affect the generation of Aβ.
Nesic I, Guix FX, Vennekens K, Michaki V, Van Veldhoven PP, Feiguin F, De Strooper B, Dotti CG, Wahle T. Nesic I, et al. Among authors: guix fx. Aging Cell. 2012 Feb;11(1):63-72. doi: 10.1111/j.1474-9726.2011.00760.x. Epub 2011 Nov 28. Aging Cell. 2012. PMID: 22023223 Free article.
Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.
Michaki V, Guix FX, Vennekens K, Munck S, Dingwall C, Davis JB, Townsend DM, Tew KD, Feiguin F, De Strooper B, Dotti CG, Wahle T. Michaki V, et al. Among authors: guix fx. J Biol Chem. 2012 Jan 6;287(2):1100-11. doi: 10.1074/jbc.M111.288258. Epub 2011 Nov 15. J Biol Chem. 2012. PMID: 22086926 Free PMC article.
Prodromal Alzheimer's Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer's Pathology.
de Vidania S, Palomares-Perez I, Frank-García A, Saito T, Saido TC, Draffin J, Szaruga M, Chávez-Gutierrez L, Calero M, Medina M, Guix FX, Dotti CG. de Vidania S, et al. Among authors: guix fx. Front Neurosci. 2020 Dec 3;14:562581. doi: 10.3389/fnins.2020.562581. eCollection 2020. Front Neurosci. 2020. PMID: 33343276 Free PMC article.
Cognitive decline in diabetic mice predisposed to Alzheimer's disease is greater than in wild type.
Carús-Cadavieco M, Berenguer López I, Montoro Canelo A, Serrano-Lope MA, González-de la Fuente S, Aguado B, Fernández-Rodrigo A, Saido TC, Frank García A, Venero C, Esteban JA, Guix F, Dotti CG. Carús-Cadavieco M, et al. Life Sci Alliance. 2023 Apr 14;6(6):e202201789. doi: 10.26508/lsa.202201789. Print 2023 Jun. Life Sci Alliance. 2023. PMID: 37059474 Free PMC article.
30 results