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Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.
Gholamin S, Mitra SS, Feroze AH, Liu J, Kahn SA, Zhang M, Esparza R, Richard C, Ramaswamy V, Remke M, Volkmer AK, Willingham S, Ponnuswami A, McCarty A, Lovelace P, Storm TA, Schubert S, Hutter G, Narayanan C, Chu P, Raabe EH, Harsh G 4th, Taylor MD, Monje M, Cho YJ, Majeti R, Volkmer JP, Fisher PG, Grant G, Steinberg GK, Vogel H, Edwards M, Weissman IL, Cheshier SH. Gholamin S, et al. Among authors: fisher pg. Sci Transl Med. 2017 Mar 15;9(381):eaaf2968. doi: 10.1126/scitranslmed.aaf2968. Sci Transl Med. 2017. PMID: 28298418 Free article.
Loss of SMARCB1/INI1 expression in poorly differentiated chordomas.
Mobley BC, McKenney JK, Bangs CD, Callahan K, Yeom KW, Schneppenheim R, Hayden MG, Cherry AM, Gokden M, Edwards MS, Fisher PG, Vogel H. Mobley BC, et al. Among authors: fisher pg. Acta Neuropathol. 2010 Dec;120(6):745-53. doi: 10.1007/s00401-010-0767-x. Epub 2010 Oct 30. Acta Neuropathol. 2010. PMID: 21057957
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma.
Monje M, Mitra SS, Freret ME, Raveh TB, Kim J, Masek M, Attema JL, Li G, Haddix T, Edwards MS, Fisher PG, Weissman IL, Rowitch DH, Vogel H, Wong AJ, Beachy PA. Monje M, et al. Among authors: fisher pg. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4453-8. doi: 10.1073/pnas.1101657108. Epub 2011 Mar 1. Proc Natl Acad Sci U S A. 2011. PMID: 21368213 Free PMC article.
299 results