Zou MF - Search Results

1

Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D₂ Receptor (D₂R) Biased Agonism.

Bonifazi A, Yano H, Ellenberger MP, Muller L, Kumar V, Zou MF, Cai NS, Guerrero AM, Woods AS, Shi L, Newman AH. Bonifazi A, et al. Among authors: zou mf. J Med Chem. 2017 Apr 13;60(7):2890-2907. doi: 10.1021/acs.jmedchem.6b01875. Epub 2017 Mar 16. J Med Chem. 2017. PMID: 28300398 Free PMC article.

2

Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.

Zou MF, Kopajtic T, Katz JL, Newman AH. Zou MF, et al. J Med Chem. 2003 Jul 3;46(14):2908-16. doi: 10.1021/jm0300375. J Med Chem. 2003. PMID: 12825932

3

Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.

Zou MF, Cao J, Kopajtic T, Desai RI, Katz JL, Newman AH. Zou MF, et al. J Med Chem. 2006 Oct 19;49(21):6391-9. doi: 10.1021/jm060762q. J Med Chem. 2006. PMID: 17034144

4

Structure-activity relationships in a novel series of 7-substituted-aryl quinolines and 5-substituted-aryl benzothiazoles at the metabotropic glutamate receptor subtype 5.

Zhang P, Zou MF, Rodriguez AL, Conn PJ, Newman AH. Zhang P, et al. Among authors: zou mf. Bioorg Med Chem. 2010 May 1;18(9):3026-35. doi: 10.1016/j.bmc.2010.03.053. Epub 2010 Mar 27. Bioorg Med Chem. 2010. PMID: 20382541 Free PMC article.

5

Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.

Zou MF, Keck TM, Kumar V, Donthamsetti P, Michino M, Burzynski C, Schweppe C, Bonifazi A, Free RB, Sibley DR, Janowsky A, Shi L, Javitch JA, Newman AH. Zou MF, et al. J Med Chem. 2016 Apr 14;59(7):2973-88. doi: 10.1021/acs.jmedchem.5b01612. Epub 2016 Apr 1. J Med Chem. 2016. PMID: 27035329 Free PMC article.

6

Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.

Zou MF, Cao J, Abramyan AM, Kopajtic T, Zanettini C, Guthrie DA, Rais R, Slusher BS, Shi L, Loland CJ, Newman AH. Zou MF, et al. J Med Chem. 2017 Dec 28;60(24):10172-10187. doi: 10.1021/acs.jmedchem.7b01454. Epub 2017 Dec 11. J Med Chem. 2017. PMID: 29227643 Free PMC article.

7

Enantioselective synthesis of S-(+)-2beta-carboalkoxy-3alpha-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter.

Zou MF, Agoston GE, Belov Y, Kopajtic T, Katz JL, Newman AH. Zou MF, et al. Bioorg Med Chem Lett. 2002 May 6;12(9):1249-52. doi: 10.1016/s0960-894x(02)00155-5. Bioorg Med Chem Lett. 2002. PMID: 11965364

8

Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter.

Cha JH, Zou MF, Adkins EM, Rasmussen SG, Loland CJ, Schoenenberger B, Gether U, Newman AH. Cha JH, et al. Among authors: zou mf. J Med Chem. 2005 Dec 1;48(24):7513-6. doi: 10.1021/jm050431y. J Med Chem. 2005. PMID: 16302792

9

Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.

Kulkarni SS, Zou MF, Cao J, Deschamps JR, Rodriguez AL, Conn PJ, Newman AH. Kulkarni SS, et al. Among authors: zou mf. J Med Chem. 2009 Jun 11;52(11):3563-75. doi: 10.1021/jm900172f. J Med Chem. 2009. PMID: 19445453 Free PMC article.

10

Design and synthesis of substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5.

Zou MF, Cao J, Rodriguez AL, Conn PJ, Newman AH. Zou MF, et al. Bioorg Med Chem Lett. 2011 May 1;21(9):2650-4. doi: 10.1016/j.bmcl.2010.12.110. Epub 2010 Dec 28. Bioorg Med Chem Lett. 2011. PMID: 21295978 Free PMC article.

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