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Page 1
The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.
von Heyking K, Calzada-Wack J, Göllner S, Neff F, Schmidt O, Hensel T, Schirmer D, Fasan A, Esposito I, Müller-Tidow C, Sorensen PH, Burdach S, Richter GHS. von Heyking K, et al. Among authors: richter ghs. Mol Oncol. 2017 Sep;11(9):1288-1301. doi: 10.1002/1878-0261.12057. Epub 2017 Aug 21. Mol Oncol. 2017. PMID: 28319320 Free PMC article.
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.
Grunewald TG, Diebold I, Esposito I, Plehm S, Hauer K, Thiel U, da Silva-Buttkus P, Neff F, Unland R, Müller-Tidow C, Zobywalski C, Lohrig K, Lewandrowski U, Sickmann A, Prazeres da Costa O, Görlach A, Cossarizza A, Butt E, Richter GH, Burdach S. Grunewald TG, et al. Mol Cancer Res. 2012 Jan;10(1):52-65. doi: 10.1158/1541-7786.MCR-11-0524. Epub 2011 Nov 11. Mol Cancer Res. 2012. PMID: 22080479 Free article.
Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis.
Schmidt O, Nehls N, Prexler C, von Heyking K, Groll T, Pardon K, Garcia HD, Hensel T, Gürgen D, Henssen AG, Eggert A, Steiger K, Burdach S, Richter GHS. Schmidt O, et al. Among authors: richter ghs. J Exp Clin Cancer Res. 2021 Oct 15;40(1):322. doi: 10.1186/s13046-021-02125-z. J Exp Clin Cancer Res. 2021. PMID: 34654445 Free PMC article.
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.
Richter GH, Plehm S, Fasan A, Rössler S, Unland R, Bennani-Baiti IM, Hotfilder M, Löwel D, von Luettichau I, Mossbrugger I, Quintanilla-Martinez L, Kovar H, Staege MS, Müller-Tidow C, Burdach S. Richter GH, et al. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5324-9. doi: 10.1073/pnas.0810759106. Epub 2009 Mar 16. Proc Natl Acad Sci U S A. 2009. PMID: 19289832 Free PMC article.
Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.
Agelopoulos K, Richter GH, Schmidt E, Dirksen U, von Heyking K, Moser B, Klein HU, Kontny U, Dugas M, Poos K, Korsching E, Buch T, Weckesser M, Schulze I, Besoke R, Witten A, Stoll M, Köhler G, Hartmann W, Wardelmann E, Rossig C, Baumhoer D, Jürgens H, Burdach S, Berdel WE, Müller-Tidow C. Agelopoulos K, et al. Clin Cancer Res. 2015 Nov 1;21(21):4935-46. doi: 10.1158/1078-0432.CCR-14-2744. Epub 2015 Jul 15. Clin Cancer Res. 2015. PMID: 26179511 Free article.
Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T cells specifically inhibit Ewing sarcoma growth in vitro and in vivo.
Blaeschke F, Thiel U, Kirschner A, Thiede M, Rubio RA, Schirmer D, Kirchner T, Richter GHS, Mall S, Klar R, Riddell S, Busch DH, Krackhardt A, Grunewald TG, Burdach S. Blaeschke F, et al. Among authors: richter ghs. Oncotarget. 2016 Jul 12;7(28):43267-43280. doi: 10.18632/oncotarget.9218. Oncotarget. 2016. PMID: 27281613 Free PMC article.
47 results