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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Schweiger M, Romauch M, Schreiber R, Grabner GF, Hütter S, Kotzbeck P, Benedikt P, Eichmann TO, Yamada S, Knittelfelder O, Diwoky C, Doler C, Mayer N, De Cecco W, Breinbauer R, Zimmermann R, Zechner R. Schweiger M, et al. Among authors: zechner r. Nat Commun. 2017 Mar 22;8:14859. doi: 10.1038/ncomms14859. Nat Commun. 2017. PMID: 28327588 Free PMC article.
Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity.
Strauss JG, Zimmermann R, Hrzenjak A, Zhou Y, Kratky D, Levak-Frank S, Kostner GM, Zechner R, Frank S. Strauss JG, et al. Among authors: zechner r. Biochem J. 2002 Nov 15;368(Pt 1):69-79. doi: 10.1042/BJ20020306. Biochem J. 2002. PMID: 12164779 Free PMC article.
Letting lipids go: hormone-sensitive lipase.
Haemmerle G, Zimmermann R, Zechner R. Haemmerle G, et al. Among authors: zechner r. Curr Opin Lipidol. 2003 Jun;14(3):289-97. doi: 10.1097/00041433-200306000-00009. Curr Opin Lipidol. 2003. PMID: 12840660 Review.
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.
Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A, Zechner R. Zimmermann R, et al. Among authors: zechner r. Science. 2004 Nov 19;306(5700):1383-6. doi: 10.1126/science.1100747. Science. 2004. PMID: 15550674
249 results