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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands.
Czimmerer Z, Halasz L, Daniel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyak Z, Fenyvesi F, Varadi J, Poliska S, Hajas G, Szatmari I, Glass CK, Bacsi A, Nagy L. Czimmerer Z, et al. Immunity. 2022 Nov 8;55(11):2006-2026.e6. doi: 10.1016/j.immuni.2022.10.004. Epub 2022 Nov 1. Immunity. 2022. PMID: 36323312 Free PMC article.
Editorial: Transcriptional regulation of macrophage function.
Czimmerer Z, Patsalos A, Hoeksema MA. Czimmerer Z, et al. Among authors: hoeksema ma. Front Immunol. 2023 Nov 2;14:1321064. doi: 10.3389/fimmu.2023.1321064. eCollection 2023. Front Immunol. 2023. PMID: 38022640 Free PMC article. No abstract available.
Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.
Wijnands KA, Hoeksema MA, Meesters DM, van den Akker NM, Molin DG, Briedé JJ, Ghosh M, Köhler SE, van Zandvoort MA, de Winther MP, Buurman WA, Lamers WH, Poeze M. Wijnands KA, et al. Among authors: hoeksema ma. PLoS One. 2014 Jan 21;9(1):e86135. doi: 10.1371/journal.pone.0086135. eCollection 2014. PLoS One. 2014. PMID: 24465919 Free PMC article.
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Hoeksema MA, et al. EMBO Mol Med. 2014 Sep;6(9):1124-32. doi: 10.15252/emmm.201404170. EMBO Mol Med. 2014. PMID: 25007801 Free PMC article.
Macrophage polarization: the epigenetic point of view.
Van den Bossche J, Neele AE, Hoeksema MA, de Winther MP. Van den Bossche J, et al. Among authors: hoeksema ma. Curr Opin Lipidol. 2014 Oct;25(5):367-73. doi: 10.1097/MOL.0000000000000109. Curr Opin Lipidol. 2014. PMID: 25188918 Review.
Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.
Van den Bossche J, Neele AE, Hoeksema MA, de Heij F, Boshuizen MC, van der Velden S, de Boer VC, Reedquist KA, de Winther MP. Van den Bossche J, et al. Among authors: hoeksema ma. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):396-402. doi: 10.1016/j.bbrc.2014.11.029. Epub 2014 Nov 18. Biochem Biophys Res Commun. 2014. PMID: 25446073
42 results