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Page 1
PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia.
Bernelot Moens SJ, Neele AE, Kroon J, van der Valk FM, Van den Bossche J, Hoeksema MA, Hoogeveen RM, Schnitzler JG, Baccara-Dinet MT, Manvelian G, de Winther MPJ, Stroes ESG. Bernelot Moens SJ, et al. Among authors: van den bossche j, van der valk fm. Eur Heart J. 2017 May 21;38(20):1584-1593. doi: 10.1093/eurheartj/ehx002. Eur Heart J. 2017. PMID: 28329114
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality.
Boon MR, van den Berg SA, Wang Y, van den Bossche J, Karkampouna S, Bauwens M, De Saint-Hubert M, van der Horst G, Vukicevic S, de Winther MP, Havekes LM, Jukema JW, Tamsma JT, van der Pluijm G, van Dijk KW, Rensen PC. Boon MR, et al. Among authors: van den bossche j, van der pluijm g, van dijk kw, van den berg sa, van der horst g. PLoS One. 2013 Sep 16;8(9):e74083. doi: 10.1371/journal.pone.0074083. eCollection 2013. PLoS One. 2013. PMID: 24066098 Free PMC article.
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Hoeksema MA, et al. Among authors: van den bossche j, van der velden s. EMBO Mol Med. 2014 Sep;6(9):1124-32. doi: 10.15252/emmm.201404170. EMBO Mol Med. 2014. PMID: 25007801 Free PMC article.
Macrophage polarization: the epigenetic point of view.
Van den Bossche J, Neele AE, Hoeksema MA, de Winther MP. Van den Bossche J, et al. Curr Opin Lipidol. 2014 Oct;25(5):367-73. doi: 10.1097/MOL.0000000000000109. Curr Opin Lipidol. 2014. PMID: 25188918 Review.
Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.
Van den Bossche J, Neele AE, Hoeksema MA, de Heij F, Boshuizen MC, van der Velden S, de Boer VC, Reedquist KA, de Winther MP. Van den Bossche J, et al. Among authors: van der velden s. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):396-402. doi: 10.1016/j.bbrc.2014.11.029. Epub 2014 Nov 18. Biochem Biophys Res Commun. 2014. PMID: 25446073
IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment.
Hoeksema MA, Scicluna BP, Boshuizen MC, van der Velden S, Neele AE, Van den Bossche J, Matlung HL, van den Berg TK, Goossens P, de Winther MP. Hoeksema MA, et al. Among authors: van den bossche j, van den berg tk, van der velden s. J Immunol. 2015 Apr 15;194(8):3909-16. doi: 10.4049/jimmunol.1402077. Epub 2015 Mar 6. J Immunol. 2015. PMID: 25750432
Metabolic-epigenetic crosstalk in macrophage activation.
Baardman J, Licht I, de Winther MP, Van den Bossche J. Baardman J, et al. Among authors: van den bossche j. Epigenomics. 2015 Oct;7(7):1155-64. doi: 10.2217/epi.15.71. Epub 2015 Nov 20. Epigenomics. 2015. PMID: 26585710
148 results