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Immunological memory to hyperphosphorylated tau in asymptomatic individuals.
Pascual G, Wadia JS, Zhu X, Keogh E, Kükrer B, van Ameijde J, Inganäs H, Siregar B, Perdok G, Diefenbach O, Nahar T, Sprengers I, Koldijk MH, der Linden EC, Peferoen LA, Zhang H, Yu W, Li X, Wagner M, Moreno V, Kim J, Costa M, West K, Fulton Z, Chammas L, Luckashenak N, Fletcher L, Holland T, Arnold C, Anthony Williamson R, Hoozemans JJ, Apetri A, Bard F, Wilson IA, Koudstaal W, Goudsmit J. Pascual G, et al. Among authors: li x. Acta Neuropathol. 2017 May;133(5):767-783. doi: 10.1007/s00401-017-1705-y. Epub 2017 Mar 24. Acta Neuropathol. 2017. PMID: 28341999 Free PMC article.
Naturally occurring antibodies isolated from PD patients inhibit synuclein seeding in vitro and recognize Lewy pathology.
Li X, Koudstaal W, Fletcher L, Costa M, van Winsen M, Siregar B, Inganäs H, Kim J, Keogh E, Macedo J, Holland T, Perry S, Bard F, Hoozemans JJ, Goudsmit J, Apetri A, Pascual G. Li X, et al. Acta Neuropathol. 2019 May;137(5):825-836. doi: 10.1007/s00401-019-01974-5. Epub 2019 Feb 25. Acta Neuropathol. 2019. PMID: 30805666 Free PMC article.
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