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Higher levels of IL-6, CD4 turnover and Treg frequency are already present before cART in HIV-infected subjects with later low CD4 recovery.
Rosado-Sánchez I, Jarrín I, Pozo-Balado MM, de Pablo-Bernal RS, Herrero-Fernández I, Alvarez-Ríos AI, Rodríguez-Gallego E, Genebat M, Vera M, Berenguer J, Martín ML, Bernal E, Vidal F, Blanco J, Leal M, Pacheco YM. Rosado-Sánchez I, et al. Among authors: pacheco ym. Antiviral Res. 2017 Jun;142:76-82. doi: 10.1016/j.antiviral.2017.03.015. Epub 2017 Mar 24. Antiviral Res. 2017. PMID: 28343846
Differential alterations of the CD4 and CD8 T cell subsets in HIV-infected patients on highly active antiretroviral therapy with low CD4 T cell restoration.
Méndez-Lagares G, García-Pergañeda A, del Mar del Pozo-Balado M, Genebat M, Ruiz-Mateos E, García García M, Muñoz-Fernández MÁ, Pacheco YM, Leal M. Méndez-Lagares G, et al. Among authors: pacheco ym. J Antimicrob Chemother. 2012 May;67(5):1228-37. doi: 10.1093/jac/dkr594. Epub 2012 Jan 27. J Antimicrob Chemother. 2012. PMID: 22287235
Severe immune dysregulation affects CD4⁺CD25(hi)FoxP3⁺ regulatory T cells in HIV-infected patients with low-level CD4 T-cell repopulation despite suppressive highly active antiretroviral therapy.
Méndez-Lagares G, Pozo-Balado MM, Genebat M, García Pergañeda A, Leal M, Pacheco YM. Méndez-Lagares G, et al. Among authors: pacheco ym. J Infect Dis. 2012 May 15;205(10):1501-9. doi: 10.1093/infdis/jis230. Epub 2012 Mar 28. J Infect Dis. 2012. PMID: 22457273
Detectable viral load aggravates immunosenescence features of CD8 T-cell subsets in vertically HIV-infected children.
Díaz L, Méndez-Lagares G, Correa-Rocha R, Pacheco YM, Ferrando-Martínez S, Ruiz-Mateos E, del Mar del Pozo-Balado M, León JA, Gurbindo MD, Isabel de José M, Leal M, Muñoz-Fernández MÁ. Díaz L, et al. Among authors: pacheco ym. J Acquir Immune Defic Syndr. 2012 Aug 15;60(5):447-54. doi: 10.1097/QAI.0b013e318259254f. J Acquir Immune Defic Syndr. 2012. PMID: 22549383
83 results