Malley M - Search Results

1

Studies directed toward ascertaining the active conformation of 1,4-dihydropyridine calcium entry blockers.

Rovnyak G, Andersen N, Gougoutas J, Hedberg A, Kimball SD, Malley M, Moreland S, Porubcan M, Pudzianowski A. Rovnyak G, et al. Among authors: malley m. J Med Chem. 1988 May;31(5):936-44. doi: 10.1021/jm00400a008. J Med Chem. 1988. PMID: 2834556

2

Active conformation of 1,4-dihydropyridine calcium entry blockers. Effect of size of 2-aryl substituent on rotameric equilibria and receptor binding.

Rovnyak G, Andersen N, Gougoutas J, Hedberg A, Kimball SD, Malley M, Moreland S, Porubcan M, Pudzianowski A. Rovnyak G, et al. Among authors: malley m. J Med Chem. 1991 Aug;34(8):2521-4. doi: 10.1021/jm00112a030. J Med Chem. 1991. PMID: 1652021

3

Calcium entry blockers and activators: conformational and structural determinants of dihydropyrimidine calcium channel modulators.

Rovnyak GC, Kimball SD, Beyer B, Cucinotta G, DiMarco JD, Gougoutas J, Hedberg A, Malley M, McCarthy JP, Zhang R, et al. Rovnyak GC, et al. Among authors: malley m. J Med Chem. 1995 Jan 6;38(1):119-29. doi: 10.1021/jm00001a017. J Med Chem. 1995. PMID: 7837222

4

Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents.

Rovnyak GC, Atwal KS, Hedberg A, Kimball SD, Moreland S, Gougoutas JZ, O'Reilly BC, Schwartz J, Malley MF. Rovnyak GC, et al. Among authors: malley mf. J Med Chem. 1992 Aug 21;35(17):3254-63. doi: 10.1021/jm00095a023. J Med Chem. 1992. PMID: 1387168

5

Benzazepinone calcium channel blockers. 3. Synthesis and structure-activity studies of 3-alkylbenzazepinones.

Das J, Floyd DM, Kimball SD, Duff KJ, Vu TC, Lago MW, Moquin RV, Lee VG, Gougoutas JZ, Malley MF, et al. Das J, et al. Among authors: malley mf. J Med Chem. 1992 Feb 21;35(4):773-80. doi: 10.1021/jm00082a019. J Med Chem. 1992. PMID: 1542103

6

Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.

Atwal KS, Rovnyak GC, Schwartz J, Moreland S, Hedberg A, Gougoutas JZ, Malley MF, Floyd DM. Atwal KS, et al. Among authors: malley mf. J Med Chem. 1990 May;33(5):1510-5. doi: 10.1021/jm00167a035. J Med Chem. 1990. PMID: 2329573

7

Dihydropyrimidine calcium channel blockers. 2. 3-substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.

Atwal KS, Rovnyak GC, Kimball SD, Floyd DM, Moreland S, Swanson BN, Gougoutas JZ, Schwartz J, Smillie KM, Malley MF. Atwal KS, et al. Among authors: malley mf. J Med Chem. 1990 Sep;33(9):2629-35. doi: 10.1021/jm00171a044. J Med Chem. 1990. PMID: 2391701

8

Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones.

Barrish JC, Spergel SH, Moreland S, Grover G, Hedberg SA, Pudzianowski AT, Gougoutas JZ, Malley MF. Barrish JC, et al. Among authors: malley mf. Bioorg Med Chem. 1993 Oct;1(4):309-25. doi: 10.1016/s0968-0896(00)82135-5. Bioorg Med Chem. 1993. PMID: 8081861

9

A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes.

Bisaha SN, Malley MF, Pudzianowski A, Monshizadegan H, Wang P, Madsen CS, Gougoutas JZ, Stein PD. Bisaha SN, et al. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2749-51. doi: 10.1016/j.bmcl.2005.03.115. Bioorg Med Chem Lett. 2005. PMID: 15878269

10

Novel synthesis of the hexahydroimidazo[1,5b]isoquinoline scaffold: application to the synthesis of glucocorticoid receptor modulators.

Xiao HY, Wu DR, Malley MF, Gougoutas JZ, Habte SF, Cunningham MD, Somerville JE, Dodd JH, Barrish JC, Nadler SG, Dhar TG. Xiao HY, et al. J Med Chem. 2010 Feb 11;53(3):1270-80. doi: 10.1021/jm901551w. J Med Chem. 2010. PMID: 20047280

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