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Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.
Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR. Mariño E, et al. Among authors: macia l. Nat Immunol. 2017 May;18(5):552-562. doi: 10.1038/ni.3713. Epub 2017 Mar 27. Nat Immunol. 2017. PMID: 28346408
A macrocyclic fluorescent probe for the detection of citrate.
Butler SM, Hountondji M, Berry SN, Tan J, Macia L, Jolliffe KA. Butler SM, et al. Among authors: macia l. Org Biomol Chem. 2023 Nov 1;21(42):8548-8553. doi: 10.1039/d3ob01442h. Org Biomol Chem. 2023. PMID: 37846461
The role of short-chain fatty acids in health and disease.
Tan J, McKenzie C, Potamitis M, Thorburn AN, Mackay CR, Macia L. Tan J, et al. Among authors: macia l. Adv Immunol. 2014;121:91-119. doi: 10.1016/B978-0-12-800100-4.00003-9. Adv Immunol. 2014. PMID: 24388214 Review.
Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.
Macia L, Tan J, Vieira AT, Leach K, Stanley D, Luong S, Maruya M, Ian McKenzie C, Hijikata A, Wong C, Binge L, Thorburn AN, Chevalier N, Ang C, Marino E, Robert R, Offermanns S, Teixeira MM, Moore RJ, Flavell RA, Fagarasan S, Mackay CR. Macia L, et al. Nat Commun. 2015 Apr 1;6:6734. doi: 10.1038/ncomms7734. Nat Commun. 2015. PMID: 25828455 Free article.
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites.
Thorburn AN, McKenzie CI, Shen S, Stanley D, Macia L, Mason LJ, Roberts LK, Wong CH, Shim R, Robert R, Chevalier N, Tan JK, Mariño E, Moore RJ, Wong L, McConville MJ, Tull DL, Wood LG, Murphy VE, Mattes J, Gibson PG, Mackay CR. Thorburn AN, et al. Among authors: macia l. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320. Nat Commun. 2015. PMID: 26102221 Free article.
126 results