Roué G - Search Results

1

Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma.

Balsas P, Esteve-Arenys A, Roldán J, Jiménez L, Rodríguez V, Valero JG, Chamorro-Jorganes A, de la Bellacasa RP, Teixidó J, Matas-Céspedes A, Moros A, Martínez A, Campo E, Sáez-Borderías A, Borrell JI, Pérez-Galán P, Colomer D, Roué G. Balsas P, et al. Among authors: roue g. J Hematol Oncol. 2017 Mar 31;10(1):80. doi: 10.1186/s13045-017-0447-6. J Hematol Oncol. 2017. PMID: 28359287 Free PMC article.

2

RHOA Therapeutic Targeting in Hematological Cancers.

Santos JC, Profitós-Pelejà N, Sánchez-Vinces S, Roué G. Santos JC, et al. Among authors: roue g. Cells. 2023 Jan 28;12(3):433. doi: 10.3390/cells12030433. Cells. 2023. PMID: 36766776 Free PMC article. Review.

3

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status.

Pérez-Galán P, Roué G, Villamor N, Montserrat E, Campo E, Colomer D. Pérez-Galán P, et al. Among authors: roue g. Blood. 2006 Jan 1;107(1):257-64. doi: 10.1182/blood-2005-05-2091. Epub 2005 Sep 15. Blood. 2006. PMID: 16166592 Free article.

4

The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak.

Pérez-Galán P, Roué G, Villamor N, Campo E, Colomer D. Pérez-Galán P, et al. Among authors: roue g. Blood. 2007 May 15;109(10):4441-9. doi: 10.1182/blood-2006-07-034173. Epub 2007 Jan 16. Blood. 2007. PMID: 17227835 Free article.

5

Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level.

Roué G, Pérez-Galán P, López-Guerra M, Villamor N, Campo E, Colomer D. Roué G, et al. J Immunol. 2007 Feb 1;178(3):1923-30. doi: 10.4049/jimmunol.178.3.1923. J Immunol. 2007. PMID: 17237443

6

Cyclin D1 mediates resistance to apoptosis through upregulation of molecular chaperones and consequent redistribution of cell death regulators.

Roué G, Pichereau V, Lincet H, Colomer D, Sola B. Roué G, et al. Oncogene. 2008 Aug 21;27(36):4909-20. doi: 10.1038/onc.2008.126. Epub 2008 Apr 28. Oncogene. 2008. PMID: 18438428

7

BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.

Pérez-Galán P, Roué G, López-Guerra M, Nguyen M, Villamor N, Montserrat E, Shore GC, Campo E, Colomer D. Pérez-Galán P, et al. Among authors: roue g. Leukemia. 2008 Sep;22(9):1712-20. doi: 10.1038/leu.2008.175. Epub 2008 Jul 3. Leukemia. 2008. PMID: 18596739

8

Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling.

Roué G, López-Guerra M, Milpied P, Pérez-Galán P, Villamor N, Montserrat E, Campo E, Colomer D. Roué G, et al. Clin Cancer Res. 2008 Nov 1;14(21):6907-15. doi: 10.1158/1078-0432.CCR-08-0388. Clin Cancer Res. 2008. PMID: 18980985

9

p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

López-Guerra M, Roué G, Pérez-Galán P, Alonso R, Villamor N, Montserrat E, Campo E, Colomer D. López-Guerra M, et al. Among authors: roue g. Clin Cancer Res. 2009 Apr 15;15(8):2767-76. doi: 10.1158/1078-0432.CCR-08-2382. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351760

10

In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.

Mollinedo F, de la Iglesia-Vicente J, Gajate C, Estella-Hermoso de Mendoza A, Villa-Pulgarin JA, de Frias M, Roué G, Gil J, Colomer D, Campanero MA, Blanco-Prieto MJ. Mollinedo F, et al. Among authors: roue g. Clin Cancer Res. 2010 Apr 1;16(7):2046-54. doi: 10.1158/1078-0432.CCR-09-2456. Epub 2010 Mar 16. Clin Cancer Res. 2010. PMID: 20233887 Free article.

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