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Multidrug Analyses in Patients Distinguish Efficacious Cancer Agents Based on Both Tumor Cell Killing and Immunomodulation.
Frazier JP, Bertout JA, Kerwin WS, Moreno-Gonzalez A, Casalini JR, Grenley MO, Beirne E, Watts KL, Keener A, Thirstrup DJ, Tretyak I, Ditzler SH, Tripp CD, Choy K, Gillings S, Breit MN, Meleo KA, Rizzo V, Herrera CL, Perry JA, Amaravadi RK, Olson JM, Klinghoffer RA. Frazier JP, et al. Among authors: olson jm. Cancer Res. 2017 Jun 1;77(11):2869-2880. doi: 10.1158/0008-5472.CAN-17-0084. Epub 2017 Mar 31. Cancer Res. 2017. PMID: 28364003 Free PMC article.
Notch signaling is not essential in sonic hedgehog-activated medulloblastoma.
Hatton BA, Villavicencio EH, Pritchard J, LeBlanc M, Hansen S, Ulrich M, Ditzler S, Pullar B, Stroud MR, Olson JM. Hatton BA, et al. Among authors: olson jm. Oncogene. 2010 Jul 1;29(26):3865-72. doi: 10.1038/onc.2010.142. Epub 2010 May 3. Oncogene. 2010. PMID: 20440271 Free PMC article.
Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.
Lee MJ, Hatton BA, Villavicencio EH, Khanna PC, Friedman SD, Ditzler S, Pullar B, Robison K, White KF, Tunkey C, LeBlanc M, Randolph-Habecker J, Knoblaugh SE, Hansen S, Richards A, Wainwright BJ, McGovern K, Olson JM. Lee MJ, et al. Among authors: olson jm. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7859-64. doi: 10.1073/pnas.1114718109. Epub 2012 May 1. Proc Natl Acad Sci U S A. 2012. PMID: 22550175 Free PMC article.
MyoD is a tumor suppressor gene in medulloblastoma.
Dey J, Dubuc AM, Pedro KD, Thirstrup D, Mecham B, Northcott PA, Wu X, Shih D, Tapscott SJ, LeBlanc M, Taylor MD, Olson JM. Dey J, et al. Among authors: olson jm. Cancer Res. 2013 Nov 15;73(22):6828-37. doi: 10.1158/0008-5472.CAN-13-0730-T. Epub 2013 Oct 3. Cancer Res. 2013. PMID: 24092238 Free PMC article.
Efficacy of cabazitaxel in mouse models of pediatric brain tumors.
Girard E, Ditzler S, Lee D, Richards A, Yagle K, Park J, Eslamy H, Bobilev D, Vrignaud P, Olson J. Girard E, et al. Neuro Oncol. 2015 Jan;17(1):107-15. doi: 10.1093/neuonc/nou163. Epub 2014 Aug 18. Neuro Oncol. 2015. PMID: 25140037 Free PMC article.
429 results