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Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice.
Yuan CC, Kazmierczak K, Liang J, Kanashiro-Takeuchi R, Irving TC, Gomes AV, Wang Y, Burghardt TP, Szczesna-Cordary D. Yuan CC, et al. Among authors: burghardt tp. Cardiovasc Res. 2017 Aug 1;113(10):1124-1136. doi: 10.1093/cvr/cvx060. Cardiovasc Res. 2017. PMID: 28371863 Free PMC article.
Single cardiac ventricular myosins are autonomous motors.
Wang Y, Yuan CC, Kazmierczak K, Szczesna-Cordary D, Burghardt TP. Wang Y, et al. Among authors: burghardt tp. Open Biol. 2018 Apr;8(4):170240. doi: 10.1098/rsob.170240. Open Biol. 2018. PMID: 29669825 Free PMC article.
107 results