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Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus.
O'Gorman WE, Hsieh EW, Savig ES, Gherardini PF, Hernandez JD, Hansmann L, Balboni IM, Utz PJ, Bendall SC, Fantl WJ, Lewis DB, Nolan GP, Davis MM. O'Gorman WE, et al. Among authors: hsieh ew. J Allergy Clin Immunol. 2015 Nov;136(5):1326-36. doi: 10.1016/j.jaci.2015.04.008. Epub 2015 May 30. J Allergy Clin Immunol. 2015. PMID: 26037552 Free PMC article.
A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.
Fernandez IZ, Baxter RM, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM, Dutmer CM, Hsieh EWY. Fernandez IZ, et al. J Exp Med. 2019 Jun 3;216(6):1255-1267. doi: 10.1084/jem.20182015. Epub 2019 Apr 30. J Exp Med. 2019. PMID: 31040184 Free PMC article.
Minimizing Batch Effects in Mass Cytometry Data.
Schuyler RP, Jackson C, Garcia-Perez JE, Baxter RM, Ogolla S, Rochford R, Ghosh D, Rudra P, Hsieh EWY. Schuyler RP, et al. Front Immunol. 2019 Oct 15;10:2367. doi: 10.3389/fimmu.2019.02367. eCollection 2019. Front Immunol. 2019. PMID: 31681275 Free PMC article. Review.
Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes.
Okamato Y, Ghosh T, Okamoto T, Schuyler RP, Seifert J, Charry LL, Visser A, Feser M, Fleischer C, Pedrick C, August J, Moss L, Bemis EA, Norris JM, Kuhn KA, Demoruelle MK, Deane KD, Ghosh D, Holers VM, Hsieh EWY. Okamato Y, et al. J Autoimmun. 2021 Feb;117:102581. doi: 10.1016/j.jaut.2020.102581. Epub 2020 Dec 9. J Autoimmun. 2021. PMID: 33310262 Free PMC article.
78 results