Hong J - Search Results

1

Synthesis and biological evaluation of largazole zinc-binding group analogs.

Kim B, Ratnayake R, Lee H, Shi G, Zeller SL, Li C, Luesch H, Hong J. Kim B, et al. Among authors: hong j. Bioorg Med Chem. 2017 Jun 15;25(12):3077-3086. doi: 10.1016/j.bmc.2017.03.071. Epub 2017 Apr 4. Bioorg Med Chem. 2017. PMID: 28416100 Free PMC article.

2

Total synthesis and molecular target of largazole, a histone deacetylase inhibitor.

Ying Y, Taori K, Kim H, Hong J, Luesch H. Ying Y, et al. Among authors: hong j. J Am Chem Soc. 2008 Jul 2;130(26):8455-9. doi: 10.1021/ja8013727. Epub 2008 May 29. J Am Chem Soc. 2008. PMID: 18507379

3

Synthesis and activity of largazole analogues with linker and macrocycle modification.

Ying Y, Liu Y, Byeon SR, Kim H, Luesch H, Hong J. Ying Y, et al. Among authors: hong j. Org Lett. 2008 Sep 18;10(18):4021-4. doi: 10.1021/ol801532s. Epub 2008 Aug 16. Org Lett. 2008. PMID: 18707106

4

Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.

Kasper AC, Moon EJ, Hu X, Park Y, Wooten CM, Kim H, Yang W, Dewhirst MW, Hong J. Kasper AC, et al. Among authors: hong j. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3783-6. doi: 10.1016/j.bmcl.2009.04.071. Epub 2009 Apr 22. Bioorg Med Chem Lett. 2009. PMID: 19423348 Free PMC article.

5

Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.

Liu Y, Salvador LA, Byeon S, Ying Y, Kwan JC, Law BK, Hong J, Luesch H. Liu Y, et al. Among authors: hong j. J Pharmacol Exp Ther. 2010 Nov;335(2):351-61. doi: 10.1124/jpet.110.172387. Epub 2010 Aug 25. J Pharmacol Exp Ther. 2010. PMID: 20739454 Free PMC article.

6

In Vitro and In Vivo Osteogenic Activity of Largazole.

Lee SU, Kwak HB, Pi SH, You HK, Byeon SR, Ying Y, Luesch H, Hong J, Kim SH. Lee SU, et al. Among authors: hong j. ACS Med Chem Lett. 2011 Mar 10;2(3):248-251. doi: 10.1021/ml1002794. ACS Med Chem Lett. 2011. PMID: 21666868 Free PMC article.

7

Largazole: from discovery to broad-spectrum therapy.

Hong J, Luesch H. Hong J, et al. Nat Prod Rep. 2012 Apr;29(4):449-56. doi: 10.1039/c2np00066k. Epub 2012 Feb 14. Nat Prod Rep. 2012. PMID: 22334030 Free PMC article. Review.

8

Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms.

Law ME, Corsino PE, Jahn SC, Davis BJ, Chen S, Patel B, Pham K, Lu J, Sheppard B, Nørgaard P, Hong J, Higgins P, Kim JS, Luesch H, Law BK. Law ME, et al. Among authors: hong j. Oncogene. 2013 Mar 7;32(10):1316-29. doi: 10.1038/onc.2012.138. Epub 2012 Apr 30. Oncogene. 2013. PMID: 22543582 Free PMC article.

9

Largazole pharmacokinetics in rats by LC-MS/MS.

Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Yu M, et al. Among authors: hong j. Mar Drugs. 2014 Mar 20;12(3):1623-40. doi: 10.3390/md12031623. Mar Drugs. 2014. PMID: 24658499 Free PMC article.

10

Evaluation of class I HDAC isoform selectivity of largazole analogues.

Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Kim B, et al. Among authors: hong j. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3728-31. doi: 10.1016/j.bmcl.2014.07.006. Epub 2014 Jul 9. Bioorg Med Chem Lett. 2014. PMID: 25070421 Free PMC article.

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